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, Volume 25, Supplement 2, pp 64–68 | Cite as

Activation of Prejunctional β-Adrenoceptors by Adrenaline Acting as a Co-transmitter

A Possible Cause of Hypertension
  • M. J. Rand
  • H. Majewski
  • L.-H. Tung
Section 1B: Hypertension

Summary

Adrenaline released into the circulation can be accumulated in sympathetic nerve endings. Release of adrenaline from the nerves enhances noradrenaline release, as adrenaline activates a local modulatory system mediated by presynaptic β-adrenoceptors. It is postulated that stress-induced adrenaline release from the adrenal gland could, through this mechanism, lead to hypertension.

Keywords

Adrenaline Sympathetic Nerve Plasma Adrenaline Sential Hypertension Human Essential Hypertension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© ADIS Press Australasia Pty Ltd (Inc. NSW) 1983

Authors and Affiliations

  • M. J. Rand
    • 1
    • 2
  • H. Majewski
    • 1
    • 2
  • L.-H. Tung
    • 1
    • 2
  1. 1.Department of PharmacologyUniversity of MelbourneMelbourneAustralia
  2. 2.Pharmakologisches Institut der UniversitätFreiburgAustralia

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