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Clinical Pharmacokinetics

, Volume 22, Issue 3, pp 211–222 | Cite as

Uses and Limitations of Positron Emission Tomography in Clinical Pharmacokinetics/Dynamics (Part I)

  • Laura L. Boles Ponto
  • James A. Ponto
Review Article Clinical Pharmacokinetic Concepts

Summary

Positron emission tomography (PET) involves imaging the biodistribution and tissue localisation of small amounts of radiolabelled biomolecules or drugs. In Part I of this article, the applications of pharmacokinetics in PET are discussed in order to derive quantitative measures of physiological function. Part II will examine the use of PET imaging as a tool to study the pharmacokinetics and pharmacodynamics of specific drugs.

Keywords

Positron emiSSIOn Tomography Positron emiSSIOn Tomography Imaging Raclopride Myocardial Oxygen Consumption Reversible Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Adis International Limited 1992

Authors and Affiliations

  • Laura L. Boles Ponto
    • 1
  • James A. Ponto
    • 1
  1. 1.PET Imaging Center, Department of RadiologyUniversity of IowaIowa CityUSA

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