Uses and Limitations of Positron Emission Tomography in Clinical Pharmacokinetics/Dynamics (Part I)
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Positron emission tomography (PET) involves imaging the biodistribution and tissue localisation of small amounts of radiolabelled biomolecules or drugs. In Part I of this article, the applications of pharmacokinetics in PET are discussed in order to derive quantitative measures of physiological function. Part II will examine the use of PET imaging as a tool to study the pharmacokinetics and pharmacodynamics of specific drugs.
KeywordsPositron emiSSIOn Tomography Positron emiSSIOn Tomography Imaging Raclopride Myocardial Oxygen Consumption Reversible Component
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