Drugs & Aging

, Volume 23, Issue 12, pp 997–1001 | Cite as

Intravenous Ibandronate in the Treatment of Osteoporosis

Profile Report
  • Katherine F. Croom
  • Lesley J. Scott
Adis Profile Report

Osteoporosis is a progressive disease characterised by decreased bone mass and disordered bone architecture, leading to fragility and an increased risk of fractures, particularly of the spine, hip and wrist.[7] When described in terms of bone mineral density (BMD), osteoporosis is defined as BMD more than 2.5 standard deviations below the mean for young normal subjects of the same gender (T score < −2.5).[7] The risk of osteoporosis increases with age and, while it occurs in both men and women, it is especially common in postmenopausal women, related to a decrease in estrogen-mediated suppression of bone resorption.[7,8] At least one in three women over the age of 50 years will experience an osteoporotic fracture.[7,8]

The main aim of treatment is to reduce the risk of fractures, which can be achieved by slowing bone loss and improving bone mass and quality.[8] Lifestyle preventive measures include dietary considerations, exercise, avoidance of smoking and limiting alcohol intake.[8]...


Bone Mineral Density Osteoporosis Bisphosphonates Alendronate Risedronate 
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Copyright information

© Adis Data Information BV 2006

Authors and Affiliations

  1. 1.Wolters Kluwer Health ¦ AdisMairangi Bay, AucklandNew Zealand
  2. 2.Editorial office of Wolters Kluwer HealthConshohockenUSA

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