Drugs & Aging

, Volume 2, Issue 6, pp 469–472 | Cite as

Is Hypertension in the Elderly Over-Treated?

  • Bodil Lernfelt
  • Sten Landahl
Leading Article


Felodipine Systolic Hypertension American Geriatrics Society Elderly Hypertensive Patient Affect Blood Pressure 
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  1. Amery A, Birkenhäger W, Brixko P, Bulpitt C, Clement D, et al. Efficacy of antihypertensive drug treatment to age, sex, blood pressure and previous cardiovascular disease in patients over the age of 60. Lancet 2: 589–592, 1986PubMedCrossRefGoogle Scholar
  2. Amery A, Birkenhäger W, Brixko P, Bulpitt C, Clement D, et al. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly Trial. Lancet 1: 1349–1354, 1985PubMedCrossRefGoogle Scholar
  3. Borhani NO. Prevalence and prognostic significance of hypertension in the elderly. Journal of the American Geriatrics Society 34: 112–114, 1986PubMedGoogle Scholar
  4. Coope J, Warrender T, McPherson K. The prognostic significance of blood pressure in the elderly. Journal of Human Hypertension 2: 79–88, 1988PubMedGoogle Scholar
  5. Coope J, Warrender T. Randomised trial of treatment of hypertension in elderly patients in primary health care. British Medical Journal 293: 1145–1151, 1986PubMedCrossRefGoogle Scholar
  6. Dahlöv B, Lindholm LH, Hansson L, Scherstén B, Ekbom T, et al. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension): Main results. Lancet 338: 1281–1285, 1991CrossRefGoogle Scholar
  7. Fletcher A E. Adverse treatment effects in the trial of the European Working Party on Hypertension in the Elderly. American Journal of Medicine 90(3A): 42S–44S, 1991PubMedCrossRefGoogle Scholar
  8. Fletcher A, Franks P, Bulpitt C. The effect of withdrawing antihypertensive therapy: a review. Journal of Hypertension 6: 431–436, 1988PubMedCrossRefGoogle Scholar
  9. Gifford RW. Isolated systolic hypertension in the elderly. Journal of the American Medical Association 247: 781–785, 1982PubMedCrossRefGoogle Scholar
  10. Harris T, Cook EF, Kannel WB, Goldman L. Proportional hazards analysis of risk factors for coronary heart disease in individuals aged 65 or older. Journal of the American Geriatrics Society 36: 1023–1028, 1988PubMedGoogle Scholar
  11. Holme I, Waaler HT. Five year mortality in the city of Bergen, Norway, according to age, sex and blood pressure. Acta Medica Scandinavia 200: 229–239, 1976CrossRefGoogle Scholar
  12. Kannel B, Gordon T. Evaluation of cardiovascular risk in the elderly: The Framingham Study. Bulletin of the New York Academy of Medicine 54: 573–591, 1978PubMedGoogle Scholar
  13. Landahl S, Bengtsson C, Sigurdsson J, Svanborg A, Svardsudd K. Age related changes in blood pressure. Hypertension 8: 1044–1049, 1986PubMedCrossRefGoogle Scholar
  14. Landahl S, Lernfelt B, Sundh V. Blood pressure and mortality in old age. Eleven year’ follow-up of a 70 year old population. Journal of Hypertension 5: 745–748, 1987PubMedCrossRefGoogle Scholar
  15. Landahl S, Edgar B, Gabrielsson M, Larsson M, Lernfelt B, et al. Pharmacokinetics and blood pressure effects of felodipine in elderly hypertensive patients. A comparison with young healthy subjects. Clinical Pharmacokinetics 14: 374–383, 1988PubMedCrossRefGoogle Scholar
  16. Lernfelt B, Landahl S, Svanborg A, Wikstrand J. Overtreatment of hypertension in the elderly? Journal of Hypertension 8: 483–490, 1990bPubMedCrossRefGoogle Scholar
  17. Lernfelt B, Landahl S, Svanborg A. Coronary heart disease at 70, 75 and 79 years of age. A longitudinal study with special reference to sex difference and mortality. Age and Ageing 19: 297–303, 1990aPubMedCrossRefGoogle Scholar
  18. Lernfelt B, Wikstrand J, Svanborg A, Landahl S. Aging and left ventricular function in old healthy people. American Journal of Cardiology 68: 547–549, 1991PubMedCrossRefGoogle Scholar
  19. Mattila K, Haavisto M, Rajala S, Heikinheimo R. Blood pressure and five year survival in the very old. British Medical Journal 296: 887–889, 1988PubMedCrossRefGoogle Scholar
  20. Messerli FH. Antihypertensive therapy. Is it different in the elderly? Drugs 39(Suppl. 2): 49–54, 1990PubMedCrossRefGoogle Scholar
  21. Messerli FH. Essential hypertension in the elderly. Triangle 24: 35–47, 1985Google Scholar
  22. Report by the Management Committee: The Australian Therapeutic Trial in Mild Hypertension. Lancet 1: 1261–1271, 1980Google Scholar
  23. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older patients with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program. Journal of the American Medical Association 265: 3255–3264, 1991CrossRefGoogle Scholar
  24. Ulemura K. International trends in cardiovascular disease in the elderly. European Heart Journal 9(Suppl. D): 1–8, 1988Google Scholar
  25. Veterans Administration Cooperative Study Group on Antihypertensive Agents. Effects of treatment on morbidity in hypertension. Influence of age, diastolic pressure and prior cardiovascular disease. Further analysis of side-effects. Circulation 45: 991–1004, 1972CrossRefGoogle Scholar
  26. Wikstrand J. Diastolic function of the hypertrophied left ventricle in primary hypertension. Clinical Physiology 6: 115–127, 1986PubMedCrossRefGoogle Scholar
  27. Wikstrand J. New concepts in the treatment of elderly hypertensive patients. American Heart Journal 116: 296–300, 1988PubMedCrossRefGoogle Scholar

Copyright information

© Adis International Limited 1992

Authors and Affiliations

  • Bodil Lernfelt
    • 1
  • Sten Landahl
    • 1
  1. 1.Department of Geriatric and Long Term Care Medicine, Vasa Hospital, Clinic IVGothenburg UniversityGothenburgSweden

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