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Valid screening questions useful to diagnose hand and forearm eczema are available in the Spanish language, a new tool for global research

Abstract

Hand eczema is an impacting cutaneous disease. Globally valid tools that help to diagnose hand and forearm eczema are required.

Objective

To validate the questions to detect hand and/or forearm eczema included in the “Nordic Occupational Skin Questionnaire” (NOSQ-2002) in the Spanish language.

Materials and methods

Aprospective pilot studywas conducted with 80 employees of a cleaning company and a retrospective one involving 2,546 individuals. The responses were analysed for sensitivity, specificity and positive and negative predictive values. The final diagnosis according to the patients’ hospital records, the specialty care records and the physical examination was taken as gold standard. The Dermatology Life Quality Index (DLQI) was also evaluated.

Results

Sensitivity and specificity, in a worst case scenario (WC) combining both questions, were 96.5% and 66.7%, respectively, and in a per protocol (PP) analysis, were 96.5% and 75.2%.

Conclusion

The questions validated detected eczema effectively, making this tool suitable for use e.g. in multicentre epidemiological studies or clinical trials.

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References

  1. Svensson Å, Lindberg M, Meding B, Sundberg K, Stenberg B. Selfreported hand eczema: symptom-based reports do not increase the validity of diagnosis. Br J Dermatol 2002; 147: 281–4.

    CAS  PubMed  Article  Google Scholar 

  2. Moberg C, Alderling M, Meding B. Hand eczema and quality of life. Br J Dermatol 2009; 161: 397–403.

    CAS  PubMed  Article  Google Scholar 

  3. Thyssen JP, Johansen JD, Linneberg A, Menné T. The epidemiology of hand eczema in the general population prevalence and main findings. Contact Dermatitis 2010; 62: 75–87.

    PubMed  Article  Google Scholar 

  4. Cvetkovski RS, Zachariae R, Jensen H, Olsen J, Johansen JD, Agner T. Prognosis of Occupational Hand Eczema. Arch Dermatol 2006; 142: 305–11.

    PubMed  Article  Google Scholar 

  5. Diepgen TL, Agner T, Aberer W, et al. Management of chronic hand eczema. Contact Dermatitis 2007; 57: 203–10.

    PubMed  Article  Google Scholar 

  6. Vermeulen R, Kromhout H, Bruynzeel DP, de Boer EM, Brunekreef B. Dermal exposure, handwashing, and hand dermatitis in the rubber manufacturing industry. Epidemiology 2001; 12: 350–4.

    CAS  PubMed  Article  Google Scholar 

  7. Vermeulen R, Kromhout H, Bruynzeel DP, de Boer EM. Ascertainment of hand dermatitis using a symptom-based questionnaire; applicability in an industrial population. Contact Dermatitis 2000; 42: 202–6.

    CAS  PubMed  Article  Google Scholar 

  8. Smit HA, Burdorf A, Coenraads PJ. Prevalence of hand dermatitis in different occupations. Int J of Epidemiology 1993; 22: 288–93.

    CAS  Article  Google Scholar 

  9. Carstensen O, Rasmussen K, Ponten A, Gruvberger B, Isaksson M, Bruze A. The validity of a questionnaire-based epidemiological study of occupational dermatosis. Contact Dermatitis 2006; 55: 295–300.

    PubMed  Article  Google Scholar 

  10. Susitaival P, Flyvholm M-A, Meding B, et al. Nordic occupational skin questionnaire (NOSQ-2002): a new tool for surveying occupational skin diseases and exposure. Contact Dermatitis 2003; 49: 70–6.

    CAS  PubMed  Article  Google Scholar 

  11. Sala-Sastre N, Herdman M, Navarro L, et al. Principles and methodology for translation and cross-cultural adaptation of the Nordic Occupational Skin Questionnaire (NOSQ-2002) to Spanish and Catalan. Contact Dermatitis 2009; 61: 109–16.

    PubMed  Article  Google Scholar 

  12. Bregnhoj A, Sosted H, Menné T, Johansen JD. Validation of selfreporting of hand eczema among Danish hairdressing apprentices. Contact Dermatitis 2011; 65: 146–50.

    PubMed  Article  Google Scholar 

  13. Sackett DL, Straus ShE, Richardson WS, Rosenberg W, Haynes RB. Medicina basada en la evidencia. Cómo practicar y enseñar la MBE. 2a ed. Ed. Harcourt 2001; 91–134.

    Google Scholar 

  14. Lewis VL, Finlay AY. Ten years experience of the Dermatology Life Quality Index (DLQI). J Investig Dermatol Symp Proc 2004; 9: 169–80.

    PubMed  Article  Google Scholar 

  15. Hongbo Y, Thomas CL, Harrison MA, Salek MS, Finlay AY. Translating the Science of Quality of Life into Practice: What Do Dermatology Life Quality Index Scores Mean? J Invest Dermatol 2005; 125: 659–64.

    CAS  PubMed  Article  Google Scholar 

  16. Basra MKA, Fenech R, Gatt RM, Salek MS, Finlay AY. The Dermatology Life Quality Index 1994–2007: a comprehensive review of validation data and clinical results. Br J Dermatol 2008; 159: 997–1035.

    CAS  PubMed  Google Scholar 

  17. Mirabelli M, Vizcaya D, Martí Margarit A, et al. Occupational risk factors for hand dermatitis in a population of professional cleaning workers in Spain. Draft for Contact Dermatitis 2012; 66:188–96.

    Article  Google Scholar 

  18. de Joode BW, Vermeulen R, Heederik D, Van Ginkel K, Kromhout H. Evaluation of 2 self-administered questionnaires to ascertain dermatitis among metal workers and its relation with exposure to metalworking fluids. Contact Dermatitis 2007; 56: 311–7.

    PubMed  Article  Google Scholar 

  19. Altman DG, Bland JM. Diagnosis tests 2: predictive values. BMJ 1994; 309: 102.

    CAS  PubMed Central  PubMed  Article  Google Scholar 

  20. Doust J. Diagnosis in general practice. Using probabilistic reasoning. BMJ 2009; 339: b3823.

    Article  Google Scholar 

  21. Potter J, Odutola J, Gonzales CA, Ward MM. Validation of English and Spanish-language versions of a screening questionnaire for rheumatoid arthritis in an underserved community. J Rheumatol 2008; 35: 1545–9.

    PubMed Central  PubMed  Google Scholar 

  22. Yost KJ, Cheville AL, Weaver AL, Al Hilli M, Dowdy SC. Development and Validation of a Self-Report Lower-Extremity Lymphedema Screening Questionnaire in Women. Phys Ther 2013; 93: 694–703.

    PubMed  Article  Google Scholar 

  23. Hamilton L, Macgregor A, Newman D, Belkhiri A, Toms A, Gaffney K. Validation of a Patient Self-Reported Screening Questionnaire for Axial Spondyloarthropathy in a UK Population. Spine (Phila Pa 1976). 2012; 38: 502–6.

    Article  Google Scholar 

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Correspondence to Ana M. Giménez-Arnau.

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Martí-Margarit, A., Manresa, J.M., Herdman, M. et al. Valid screening questions useful to diagnose hand and forearm eczema are available in the Spanish language, a new tool for global research. Eur J Dermatol 25, 145–155 (2015). https://doi.org/10.1684/ejd.2014.2485

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  • DOI: https://doi.org/10.1684/ejd.2014.2485

Key words

  • eczema
  • dermatitis
  • forearms
  • hands
  • occupation
  • occupational
  • validation
  • wrist