European Journal of Dermatology

, Volume 25, Issue 1, pp 71–73 | Cite as

Refractory metastasis of cutaneous angiosarcoma showing complete response to pazopanib

  • Susumu Fujiwara
  • Hiroshi Nagai
  • Yuji Nakamachi
  • Seiji Kawano
  • Chikako Nishigori
Correspondence
  • 37 Downloads

Keywords

Psoriasis Angiosarcoma Pazopanib Pemphigus Ground Glass Opacity 

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References

  1. 1.
    Masuzawa M, Mikami T, Numata Y, et al. Association of D2-40 and MMP-1 expression with cyst formation in lung metastatic lesions of cutaneous angiosarcoma on the scalp: immunohistochemical analysis of 23 autopsy cases. Hum Pathol 2013; 44: 2751–9.CrossRefPubMedGoogle Scholar
  2. 2.
    Ogawa K, Takahashi K, Asato Y, et al. Treatment and prognosis of angiosarcoma of the scalp and face: a retrospective analysis of 48 patients. Br J Radiol 2012; 85: e1127–33.CrossRefGoogle Scholar
  3. 3.
    Young RJ, Brown NJ, Reed MW, Hughes D, Woll PJ. Angiosarcoma. Lancet Oncol 2010; 11: 983–91.CrossRefPubMedGoogle Scholar
  4. 4.
    Rice S, Kozak KR, Mohindra P. Scalp angiosarcoma: Discussion of a management plan. Applied Radiation Oncology 2013. Available at: http://appliedradiationoncology.com/scalp-angiosarcomadiscussion-management-plan/. (accessed 12 Aug 2014).Google Scholar
  5. 5.
    van der Graaf WT, Blay JY, Chawla SP, et al. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2012; 379: 1879–86.CrossRefPubMedGoogle Scholar
  6. 6.
    Park MS, Ravi V, Araujo DM. Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/ solitary fibrous tumor. Curr Opin Oncol 2010; 22: 351–5.CrossRefPubMedGoogle Scholar
  7. 7.
    Tomita H, Koike Y, Asai M, et al. Angiosarcoma of the scalp successfully treated with pazopanib. J Am Acad Dermatol 2014; 70: e19–21.CrossRefGoogle Scholar
  8. 8.
    Fujita M, Endo Y, Fujisawa A, Tanioka M, Kabashima K, Miyachi Y. Pazopanib: an alternative in taxane-resistant cutaneous angiosarcoma. Eur J Dermatol 2014; 24: 267–8.PubMedGoogle Scholar
  9. 9.
    Ranieri G, Mammì M, Donato Di M, et al. Pazopanib a tyrosine kinase inhibitor with strong anti-angiogenic activity: a new treatment for metastatic soft tissue sarcoma. Crit Rev Oncol Hematol 2014; 89: 322–9.CrossRefPubMedGoogle Scholar
  10. 10.
    Orfao A, Garcia-Montero AC, Sanchez L, Escribano L. Recent advances in the understanding of mastocytosis: the role of KIT mutations. Br J Haematol 2007; 138: 12–30.CrossRefPubMedGoogle Scholar

Copyright information

© John Libbey Eurotext 2015

Authors and Affiliations

  • Susumu Fujiwara
    • 1
  • Hiroshi Nagai
    • 1
  • Yuji Nakamachi
    • 2
  • Seiji Kawano
    • 2
  • Chikako Nishigori
    • 1
  1. 1.Division of Dermatology, Department of Internal RelatedKobe University Graduate School of MedicineKobeJapan
  2. 2.Department of clinical LaboratoryKobe University HospitalKobeJapan

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