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Interleukin-6 and cardiac operations

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  • Published:
European Cytokine Network Aims and scope

Abstract

Interleukin (IL)-6 is a pleiotropic inflammatory cytokine with both pro- and anti-inflammatory capacities, produced by different cells and tissues, such as leukocytes, adipocytes, and endothelium. From the viewpoint of cardiologists, this cytokine is a reliable biomarker of cardiac dysfunction, occurrence of atrial fibrillation, cardiac myxoma with recurrence, remote metastasis or embolization, and atherosclerotic processes. Although IL-6 levels were detected in patients undergoing cardiac operations and reported sporadically, the perioperative kinetics of IL-6 in cardiac surgical patients was insufficiently elaborated. The influencing factors, clinical implications, and causative effects of IL-6 on clinical outcomes and potential treatment choices among cardiac surgical patients remained to be clarified as well. The purpose of this article is to discuss these aspects of IL-6 in patients undergoing a cardiac operation.

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Authors and Affiliations

  1. Department of Cardiothoracic Surgery, The First Hospital of Putian, Teaching Hospital, Fujian Medical University, Fujian Province, Putian, People’s Republic of China

    Shi-Min Yuan

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  1. Shi-Min Yuan
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Correspondence to Shi-Min Yuan.

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To cite this article: Yuan SM. Interleukin-6 and cardiac operations. Eur. Cytokine Netw. 2018; 29(1): 1-15 doi:10.1684/ecn.2018.0406

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Yuan, SM. Interleukin-6 and cardiac operations. Eur Cytokine Netw 29, 1–15 (2018). https://doi.org/10.1684/ecn.2018.0406

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