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European Journal of Dermatology

, Volume 28, Issue 5, pp 688–690 | Cite as

Psoriatic mesenchymal stem cells demonstrate an enhanced ability to differentiate into vascular endothelial cells

  • Junqin Li
  • Ling Zhou
  • Jiannan Liang
  • Yanmin Liu
  • Jiao Li
  • Hui Hou
  • Ruixia Hou
  • Xuping Niu
  • Juan Li
  • Ruifeng Liu
  • Xincheng Zhao
  • Yanfeng Meng
  • Xiaoli Yang
  • Gang Wang
  • Yu Shi
  • Erle Dang
  • Kaiming ZhangEmail author
Article
  • 2 Downloads

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References

  1. 1.
    National Psoriasis Foundation. Psoriasis statistics. Available at: www.psoriasis.org/about/stats. Accessed April 6, 2007.Google Scholar
  2. 2.
    Barton SP, Abdullah MS, Marks R. Quantification of microvascular changes in the skin in patients with psoriasis. Br J Dermatol 1992; 126: 569–74.CrossRefGoogle Scholar
  3. 3.
    Xia YP, Li B, Hylton D, Detmar M, Yancopoulos GD, Rudge JS. Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood 2003; 102: 161–8.CrossRefGoogle Scholar
  4. 4.
    Hou R, Yan H, Niu X, et al. Gene expression profile of dermal mesenchymal stem cells from patients with psoriasis. J Eur Acad Dermatol Venereol 2014; 28: 1782–91.CrossRefGoogle Scholar
  5. 5.
    Campanati A, Orciani M, Lazzarini R, et al. TNF–inhibitors reduce the pathological Th1–Th17/Th2 imbalance in cutaneous mesenchymal stem cells of psoriasis patients. Exp Dermatol 2017; 26: 319–24.CrossRefGoogle Scholar
  6. 6.
    Campanati A, Orciani M, Ganzetti G, et al. The effect of etanercept on vascular endothelial growth factor production by cutaneous mesenchymal stem cells from patients with psoriasis. J Int Med Res 2016; 44: 6–9.CrossRefGoogle Scholar
  7. 7.
    Gonzalez S, Martinez–Borra J, Del Río JS, et al. The OTF3 gene polymorphism confers susceptibility to psoriasis independent of the association of HLA–Cw*0602. J Invest Dermatol 2000; 115: 824–8.CrossRefGoogle Scholar
  8. 8.
    Sochorova R, Svecova D, Sinka L, Rybarova L. Increased endothelemia as an indirect marker of changes in the blood vessel endothelium in psoriasis. J Eur Acad Dermatol Venereol 2004; 18: 556–9.CrossRefGoogle Scholar
  9. 9.
    Heidenreich R, Rocken M, Ghoreschi K. Angiogenesis: the new potential target for the therapy of psoriasis? Drug News Perspect 2008; 21: 97–105.CrossRefGoogle Scholar
  10. 10.
    Streit M, Velasco P, Brown LF, et al. Overexpression of thrombospondin–1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas. Am J Pathol 1999; 155: 441–52.CrossRefGoogle Scholar

Copyright information

© John Libbey Eurotext 2018

Authors and Affiliations

  • Junqin Li
    • 1
  • Ling Zhou
    • 1
  • Jiannan Liang
    • 1
  • Yanmin Liu
    • 1
  • Jiao Li
    • 1
  • Hui Hou
    • 1
  • Ruixia Hou
    • 1
  • Xuping Niu
    • 1
  • Juan Li
    • 1
  • Ruifeng Liu
    • 1
  • Xincheng Zhao
    • 1
  • Yanfeng Meng
    • 1
  • Xiaoli Yang
    • 1
  • Gang Wang
    • 2
  • Yu Shi
    • 3
  • Erle Dang
    • 2
  • Kaiming Zhang
    • 1
    Email author
  1. 1.Shanxi Key Laboratory of Stem Cell for Immunological Dermatosis, Institute of DermatologyTaiyuan City Centre Hospital, No. 1 Dong San Dao XiangTaiyuanChina
  2. 2.Department of Dermatology, Xijing HospitalFourth Military Medical UniversityXi’anChina
  3. 3.Department of Hematology, Oncology and Tumor Immunology Charité University Medicine BerlinCampus Virchow HospitalBerlinGermany

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