Abstract
Objective
To investigate the effect of recurrent laryngeal nerve (RLN) identification on the complications after total thyroidectomy and lobectomy.
Methods
Total 134 consecutive patients undergoing total thyroidectomy or thyroid lobectomy from January 2003 to November 2004 were investigated retrospectively. Patients were divided into two groups: RLN identified (Group A) or not (Group B). The two groups were compared for RLN injury and hypocalcaemia.
Results
The numbers of patients and nerves at risk were 71 and 129 in Group A, and 63 and 121 in Group B, respectively. RLN injury in Group A (0) was significantly lower than that in Group B (5 [7.9%]) patients, 7 [5.8%] nerves) for the numbers of patients (P=0.016) and nerves at risk (P=0.006). Temporary hypocalcaemia was significantly higher in Group A than in Group B (14 [24.1%] vs 6 [10.3%], P=0.049). Permanent complications in Group B were significantly higher than those in Group A (13 [20.6%] vs 4 [5.6%], P=0.009).
Conclusion
RLN injury was prevented and permanent complications were decreased by identifying the whole course and branches of the recurrent laryngeal nerve during total thyroidectomy.
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References
Ardito, G., Revelli, L., D’Alatri, L., Lerro, V., Guidi, M.L., Ardito, F., 2004. Revisited anatomy of the recurrent laryngeal nerves. Am. J. Surg., 187(2):249–253. [doi:10.1016/j.amjsurg.2003.11.001]
Bergamaschi, R., Becouarn, G., Ronceray, J., 1998. Morbidity of thyroid surgery. Am. J. Surg., 176(1):71–75. [doi:10.1016/S0002-9610(98)00099-3]
Betka, J., Mrzena, L., Astl, J., Nemec, J., Vlcek, P., Taudy, M., Skrivan, J., 1997. Surgical treatment strategy for thyroid gland carcinoma nodal metastases. Eur. Arch. Otorhinolaryngol., 254(s1):169–174. [doi:10.1007/BF02439753]
Bron, L.P., O’Brien, C.J., 2004. Total thyroidectomy for clinically benign disease of the thyroid gland. Br. J. Surg., 91(5):569–574. [doi:10.1002/bjs.4507]
Dackiw, A.P.B., Rotstein, L.E., Clark, O.H., 2002. Computer-assisted evoked electromyography with stimulating surgical instruments for recurrent/external laryngeal nerve identification and preservation in thyroid and parathyroid operation. Surgery, 132(6):1100–1108. [doi:10.1067/msy.2002.128483]
Dener, C., 2002. Complication rates after operations for benign thyroid disease. Acta Otolaryngol., 122(6):679–683. [doi:10.1080/000164802320396394]
Erolu, A., Ünal, M., Kocaolu, H., 1998. Total thyroidectomy for differentiated thyroid carcinoma: primary and secondary operations. Eur. J. Surg. Oncol., 24(4):283–287. [doi:10.1016/S0748-7983(98)80007-3]
Harness, J.K., Fung, L., Thompson, N.W., Burney, R.E., McCleod, M.K., 1986. Total thyroidectomy: complications and technique. World J. Surg., 10(5):781–786. [doi:10.1007/BF01655238]
Hermann, M., Alk, G., Roka, R., Glaser, K., Freissmuth, M., 2002. Laryngeal recurrent nerve injury in surgery for benign thyroid diseases. Effect of nerve dissection and impact of individual surgeon in more than 27000 nerves at risk. Ann. Surg., 235(2):261–268. [doi:10.1097/00000658-200202000-00015]
Hisham, A.N., Lukman, M.R., 2002. Recurrent laryngeal nerve in thyroid surgery: a critical appraisal. ANZ J. Surg., 72(12):887–889. [doi:10.1046/j.1445-2197.2002.02578.x]
Lo, C.Y., 2002. Parathyroid transplantation during thyroidectomy. ANZ J. Surg., 72(12):902–907. [doi:10.1046/j.1445-2197.2002.02580.x]
Mattig, H., Bildat, D., Metzger, B., 1998. Reducing the rate of recurrent nerve paralysis by routine exposure of the nerves in thyroid gland operations. Zentralbl. Chir., 123(1):17–20.
McHenry, C.R., 2002. Patient volumes and complications in thyroid surgery. Br. J. Surg., 89(7):821–823. [doi:10.1046/j.1365-2168.2002.02145.x]
Megherbi, M.T., Graba, A., Abid, L., Oulmane, D., Saidani, M., Benabadji, R., 1992. Complications and squeal of benign thyroid surgery. J. Chir. (Paris), 129(1):41–46.
Ozbas, S., Kocak, S., Aydintug, S., Cakmak, A., Demirkıan, M.A., Wishart, G.C., 2005. Comparison of the complications of subtotal, near total and total thyroidectomy in the surgical management of multinodular goiter. Endocrine J., 52(2):199–205. [doi:10.1507/endocrj.52.199]
Pappalardo, G., Guadalaxara, A., Frattaroli, F.M., Illomei, G., Falaschi, P., 1998. Total compared with subtotal thyroidectomy in benign nodular disease: personal series and review of published reports. Eur. J. Surg., 164(7):501–506. [doi:10.1080/110241598750005840]
Pimpl, W., Rieger, R., Waclawiczek, H.W., Meiser, G., Zukriegel, M., Boeckl, O., 1992. Technique of recurrent laryngeal nerve exposure within the scope of interventions of the thyroid gland. Wien. Klin. Wochenschr., 104(15):439–442.
Rosato, L., Avenia, N., Bernante, P., De Palma, M., Gulino, G., Nasi, P.G., Pelizzo, M.R., Pezzullo, L., 2004. Complications of thyroid surgery: analysis of a multicentric study on 14934 patients operated on in Italy over 5 years. World J. Surg., 28(3):271–276. [doi:10.1007/s00268-003-6903-1]
Shaha, A.R., Jaffe, B.M., 1992. Completion thyroidectomy: a critical appraisal. Surgery, 112(6):1148–1152.
Sturniolo, G., D’Alia, C., Tonante, A., Gagliano, E., Taranto, F., Lo Schiavo, M.G., 1999. The recurrent laryngeal nerve related to thyroid surgery. Am. J. Surg., 177(6):485–488. [doi:10.1016/S0002-9610(99)00101-4]
Thomusch, O., Sekulla, C., Dralle, H., 2003. Is primary total thyroidectomy justified in benign multinodular goiter? Results of a prospective quality assurance study of 45 hospitals offering different levels of care. Der Chirurg, 74(5):437–443 (In German). [doi:10.1007/s00104-002-0605-3]
Wagner, H.E., Seiler, C., 1994. Recurrent laryngeal nerve injury after throid gland surgery. Br. J. Surg., 81(2):226–228. [doi:10.1002/bjs.1800810222]
Zambudio, A.R., Rodriguez, J., Riquelme, J., Soria, T., Canteras, M., Parrilla, P., 2004. Prospective study of postoperative complications after total thyroidectomy for multinodular goiters by surgeons with experience in endocrine surgery. Ann. Surg., 240(1):18–25. [doi:10.1097/01.sla.0000129357.58265.3c]
Zedenius, J., Wadstrom, C., Delbridge, L., 1999. Routine autotransplantation of at least one parathyroid gland during total thyroidectomy may reduce permanent hypoparathyroidism to zero. ANZ J. Surg., 69(11):794–797. [doi:10.1046/j.1440-1622.1999.01697.x]
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Canbaz, H., Dirlik, M., Colak, T. et al. Total thyroidectomy is safer with identification of recurrent laryngeal nerve. J. Zhejiang Univ. Sci. B 9, 482–488 (2008). https://doi.org/10.1631/jzus.B0820033
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DOI: https://doi.org/10.1631/jzus.B0820033