Journal of Zhejiang University SCIENCE B

, Volume 8, Issue 6, pp 398–409 | Cite as

Lipids changes in liver cancer

  • Jiang Jing-ting 
  • Xu Ning 
  • Zhang Xiao-ying 
  • Wu Chang-ping 


Liver is one of the most important organs in energy metabolism. Most plasma apolipoproteins and endogenous lipids and lipoproteins are synthesized in the liver. It depends on the integrity of liver cellular function, which ensures homeostasis of lipid and lipoprotein metabolism. When liver cancer occurs, these processes are impaired and the plasma lipid and lipoprotein patterns may be changed. Liver cancer is the fifth common malignant tumor worldwide, and is closely related to the infections of hepatitis B virus (HBV) and hepatitis C virus (HCV). HBV and HCV infections are quite common in China and other Southeast Asian countries. In addition, liver cancer is often followed by a procession of chronic hepatitis or cirrhosis, so that hepatic function is damaged obviously on these bases, which may significantly influence lipid and lipoprotein metabolism in vivo. In this review we summarize the clinical significance of lipid and lipoprotein metabolism under liver cancer.

Key words

Lipids Lipoprotein Liver cancer 

CLC number



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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • Jiang Jing-ting 
    • 1
  • Xu Ning 
    • 2
  • Zhang Xiao-ying 
    • 1
  • Wu Chang-ping 
    • 1
  1. 1.Department of Tumor Biological Treatment, the Third Affiliated HospitalSuzhou UniversityChangzhouChina
  2. 2.Institute of Laboratory MedicineLund UniversityLundSweden

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