Laser Ablation Synthesis in Solution of Nanoantimicrobials for Food Packaging Applications


Designing bioactive materials, with controlled metal ion release, exerting significant bioactivity and associated low toxicity for humans, is nowadays one of the most important challenges for the scientific community. In this work, we propose a new material combining the well-known antimicrobial properties of copper nanoparticles (CuNPs) with those of bioactive chitosan (CS), a cheap natural polymer widely exploited for its biodegradability and nontoxicity. Here, we used ultrafast femtosecond laser pulses to finely fragment, via laser ablation, a Cu solid target immersed into aqueous CS solutions. Homogeneously dispersed copper-chitosan (Cu-CS) colloids were obtained by tuning the Cu/CS molar ratios, according to the initial chitosan concentration, as well as other experimental parameters. Cu-CS colloids were characterized by several techniques, like UV-Vis and X-ray Photoelectron spectroscopies (XPS). Transmission Electron Microscopy (TEM) was used to morphologically characterize the novel nanocomposites.

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  1. [1]

    H. Huang, Q. Yuan, and X. Yang, Colloids and Surfaces B: Biointerfaces 39, 31 (2004).

    CAS  Article  Google Scholar 

  2. [2]

    P. Kaur, R. Thakur, M. Barnela, M. Chopra, A. Manuja, and A. Chaudhury, J. Chem. Technol. Biotechnol. 90, 867 (2015).

    CAS  Article  Google Scholar 

  3. [3]

    J. Barnabas, M. Miraftab, Y. Qinand, and Z. Changjun, Journal of Industrial Textiles 44, 232(2014).

  4. [4]

    M. He, L. Lu, J. Zhang, and D. Li, Sci. Bull. 60, 227 (2015).

    CAS  Article  Google Scholar 

  5. [5]

    Y. Qin, Journal of Applied Polymer Science 49, 727 (1993).

    CAS  Article  Google Scholar 

  6. [6]

    X. Wang, Y. Du, L. Fan, H. Liu, and Y. Hu, Polym. Bull. 55, 105 (2005).

    CAS  Article  Google Scholar 

  7. [7]

    M. Avella, J. J. De Vlieger, M. E. Errico, S. Fischer, P. Vacca, and M. G. Volpe, Food Chemistry 93, 467 (2005).

    CAS  Article  Google Scholar 

  8. [8]

    S. Basumallick, P. Rajasekaran, L. Tetard, and S. Santra, Journal of Nanoparticle Research 16, 2675 (2014).

    Article  Google Scholar 

  9. [9]

    J.-W. Rhim, H.-M. Park and C.-S. Ha, Progress in Polymer Science 38, 1629 (2013).

    CAS  Article  Google Scholar 

  10. [10]

    H. M. C. de Azeredo, Food Research International 42, 1240 (2009).

    Article  Google Scholar 

  11. [11]

    A. Arora and G. W. Padua, Journal of Food Science 75, R43 (2010).

  12. [12]

    A. Conte, D. Longano, C. Costa, N. Ditaranto, A. Ancona, N. Cioffi, C. Scrocco, L. Sabbatini, F. Contò, and M. A. Del Nobile, Innovative Food Science & Emerging Technologies 19, 158 (2013).

    CAS  Article  Google Scholar 

  13. [13]

    V. Amendola and M. Meneghetti, Physical Chemistry Chemical Physics 11, 3805 (2009).

    CAS  Article  Google Scholar 

  14. [14]

    G. W. Yang, Progress in Materials Science 52, 648 (2007).

    CAS  Article  Google Scholar 

  15. [15]

    D. Longano, N. Ditaranto, N. Cioffi, F. Di Niso, T. Sibillano, A. Ancona, A. Conte, M. A. Del Nobile, L. Sabbatini, and L. Torsi, Analytical and Bioanalytical Chemistry 403, 1179 (2012).

    CAS  Article  Google Scholar 

  16. [16]

    A. Ancona, M. C. Sportelli, A. Trapani, R. A. Picca, C. Palazzo, E. Bonerba, F. P. Mezzapesa, G. Tantillo, G. Trapani, and N. Cioffi, Materials Letters 136, 397 (2014).

    CAS  Article  Google Scholar 

  17. [17]

    K. Mallick, M. J. Witcomb, and M. S. Scurrell, European Polymer Journal 42, 670 (2006).

    CAS  Article  Google Scholar 

  18. [18]

    M. C. Sportelli, R. A. Picca, and N. Cioffi, in Novel Antimicrobial Agents and Strategies, edited by D. A. Phoenix, F. Harris, and S. R. Dennison (Wiley-VCH Verlag GmbH & Co. KGaA, 2014), pp. 181–218.

  19. [19]

    P. K. Dutta, J. Dutta, and V. S. Tripathi, Journal of Scientific and Industrial Research 63, 20 (2004).

    CAS  Google Scholar 

  20. [20]

    S. Ganguly, International Journal of Bioassays 2, 929 (2013).

    CAS  Google Scholar 

  21. [21]

    S. Mekahlia and B. Bouzid, Physics Procedia 2, 1045 (2009).

    CAS  Article  Google Scholar 

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Correspondence to Maria C. Sportelli.

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Sportelli, M.C., Ancona, A., Picca, R.A. et al. Laser Ablation Synthesis in Solution of Nanoantimicrobials for Food Packaging Applications. MRS Online Proceedings Library 1804, 7 (2015).

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