Challenges in fabricating graphene nanodevices for electronic DNA sequencing

Abstract

Graphene-based electronic DNA sequencing techniques have received significant attention over the past decade and are hoped to provide a new generation of portable, low-cost devices capable of rapid and accurate DNA sequencing. However, these devices are yet to demonstrate DNA sequencing. This is partly due to complex fabrication requirements resulting in low device yields and limited throughput. In this paper, we review the challenging fabrication of graphene-based electronic DNA sequencing devices. We will place a particular focus on common fabrication challenges and look toward the development of high-throughput, high-yield fabrication of these devices.

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Acknowledgments

This work was funded by the UK EPSRC (Grant No. EP/ N017188/1). JAM is a RAEng Engineering for Development Research Fellow. JPF thanks the Oxford Australia Scholarship Fund for funding.

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Correspondence to Jan A. Mol.

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Fried, J.P., Swett, J.L., Bian, X. et al. Challenges in fabricating graphene nanodevices for electronic DNA sequencing. MRS Communications 8, 703–711 (2018). https://doi.org/10.1557/mrc.2018.187

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