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Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays

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Abstract

The rolling of lipid bilayer sheets into hollow cylindrical tubules have emerged as a group of interesting supramolecular nanostructures. Here, we image the self-assembled tubules of 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphochloline (DC8,9PC) with atomic force microscopy. Nanoscale ripple structures with a periodicity of ~ 200nm in the cylindrical lipid tubules are observed. We develop two simple methods based on microfluidic networks (µFN) and surface patterning to produce two dimensional ordered arrays of parallel aligned lipid tubules on substrates.

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Authors and Affiliations

  1. Advanced Materials Processing and Analysis Center, Dept. of Mechanical, Materials, and Aerospace, Unviersity of Central Florida, 32816, Orlando, FL, USA

    Yue Zhao, Nidhi Mahajan & Jiyu Fang

Authors
  1. Yue Zhao
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  2. Nidhi Mahajan
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  3. Jiyu Fang
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Zhao, Y., Mahajan, N. & Fang, J. Self-Assembled Lipid Tubules: Synthesis, Characterization, and Ordered Arrays. MRS Online Proceedings Library 922, 502 (2006). https://doi.org/10.1557/PROC-0922-U05-02

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  • DOI: https://doi.org/10.1557/PROC-0922-U05-02

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