High performance biosensors are urgently needed from medical diagnosis, to food safety/security, to the war on bio-terrorist. The smart materials play an important role in the development of high performance sensor platform. Biosensors based on microcantilevers have very high sensitivity. The microcantilevers made of different materials, such silicon, piezoelectric and magnetostrictive materials, are discussed and compared in this paper. The magnetostrictive-based microcantilevers exhibit the best performance among all microcantilevers. A new sensor platform – magnetostrictive particles (MSPs) – is reported. The advantages of MSPs over microcantilevers are experimentally demonstrated. The MSPs are wireless/remote sensors, which makes it is possible to employ the MSP-based biosensors in different environments/media. The fabrication of MSPs in micro to nano-scale is reported. Compared with the microcantilevers, MSPs exhibit a better mass sensitivity and a higher Q value, which make the MSPs a much higher overall sensitivity.
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P. Leonard, S. Hearty, J. Brennan, L. Dunne, J. Quinn, T. Chakraborty and R. O’Kennedy, Enzyme and Microbial Tech. 32, 3 (2003).
O. Tamarin, C. Dejous, D. Rebiere, J. Pistre, S. Comeau, D. Moynet and J. Bezian, Sens. Actuators B91, 275 (2003).
R. Raiteri, M. Grattarola, H. Butt and P. Skladal, Sens. Actuators B 79, 115 (2001).
V.A. Petrenko, and V.J. Vodyanoy and J. Microbio . Meth. 53(20), 243 (2003).
N.V. Lavrik, M.J. Sepaniak and P.G. Datskos, Rev. Sci. Instrum. 75, 2229 (2004).
J. Mertz, O. Marti and J. Mlynek, Appl. Phys. Lett. 62, 2344, (1993).
A. Mehta, S. Cherian, D. Hedden and T. Thundat, Appl. Phys. Lett. 78, 637 (2001).
B. Ilic, D. Czaplewsli, H. G. Craighead, P. Neuzil, C. Campagnolo and C. Batt, Appl. Phys. Lett. 77, 450 (2000).
B. Ilic, H.G. Craighead, S. Krylov, W. Senaratne, C. Ober and P. Neuzil, J. Appl. Phys. 95, 3694 (2004).
C. Ziegler, Anal Bioanal. Chem. 379, 946 (2004).
J.W. Yi, W.Y. Shih and W. H. Shih, J. Appl. Phys. 91, 1680 (2002).
G.A. Campbell and R. Mutharasan, Sens. Actuators A 122, 326 (2005).
S.Q. Li, L. Orona, Z.M. Li, Z.-Y. Cheng, Appl. Phys. Lett. (2006).
Metglas® Solution, Honeywell (http://www.metglas.com/products/).
Guide to modern piezoelectric ceramics, Morgan Matroc, Inc.
S.Q. Li, L. Orona, L.L. Fu, Z.-Y. Cheng, MRS Proc. Vol. (2005).
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Cheng, ZY. Applications of Smart Materials in the Development of High Performance Biosensors. MRS Online Proceedings Library 888, 1006 (2005). https://doi.org/10.1557/PROC-0888-V10-06