Acta Biologica Hungarica

, Volume 59, Supplement 2, pp 13–22 | Cite as

How Messengers Modulate the Shifting of Spontaneously Generated Action Potential Into Bursts of Potentials in Central Snail Neuron?

  • M. C. TsaiEmail author


How messengers modulate the shifting of spontaneously generated action potential into bursts of potentials (BoP) is studied electrophysiologically and biochemically in RP 1 and 4 neurons of the African snail, Achatina fulica Ferussac using d- and l-amphetamine (Amp) as modulator. The stereospecific effects, extracellular and intracellular ionic effects, messenger related to enzymatic effects and membrane ionic currents effects on BoP elicited by Amp are studied. The roles of organelles, such as mitochondria, protein syntheis related endoplasmic-reticulum, on the BoP are also tested. The messengers modulated the BoP are discussed.


Amphetamine bursts of potentials messengers ionic current cAMP protein synthesis inhibitor calcium image modulation 


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© Akadémiai Kiadó, Budapest 2008

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Authors and Affiliations

  1. 1.Departments of Pharmacology, College of MedicineNational Taiwan UniversityTaipeiTaiwan

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