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Immunohistological Studies on the Distribution of Learning-Related Peptides in the Central Nervous System of Conditioned Lymnaea

Acta Biologica Hungarica volume 59, pages81–92(2008)Cite this article

Abstract

Behavioral conditioning in Lymnaea increased the amount of immunolabeling in the central nervous system for the memory-associated protein calexcitin. The staining level of anti-calexcitin positive neurons was always stronger in conditioned animals than in naïve animals. In the visuo-vestibular conditioned animals, right-parietal and visceral group neurons as well as withdrawal-related neurons were positively stained with anti-calexcitin antibody. In taste-aversion conditioned animals, right-parietal visceral G-group neurons and withdrawal-related neurons were selectively stained. These neurons are candidate neurons for modulation by these conditioning paradigms.

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Affiliations

  1. Course of Biological Science and Technology, Graduate School of High-Technology for Human Welfare, Tokai University, 317 Nishino, Numazu, 410-0321, Shizuoka, Japan

    Y. Nomura

  2. Dept.8.3-Biosciences, Zoology/Physiology, Natural Sciences and Technology III, Saarland University, Postfach 151150, D-66041, Saarbrücken, Germany

    D. Hatakeyama

  3. Department of Biological Science and Technology, School of High-Technology for Human Welfare, Tokai University, 317 Nishino, Numazu, 410-0321, Shizuoka, Japan

    T. Horikoshi & M. Sakakibara

Authors
  1. Y. Nomura
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  2. D. Hatakeyama
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  3. T. Horikoshi
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  4. M. Sakakibara
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Correspondence to M. Sakakibara.

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Nomura, Y., Hatakeyama, D., Horikoshi, T. et al. Immunohistological Studies on the Distribution of Learning-Related Peptides in the Central Nervous System of Conditioned Lymnaea. BIOLOGIA FUTURA 59, 81–92 (2008). https://doi.org/10.1556/ABiol.59.2008.Suppl.13

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Keywords

  • Calexcitin
  • visuo-vestibular conditioning
  • taste-aversion conditioning
  • immunohistochemistry
  • whole-body withdrawal response