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Acta Biologica Hungarica

, Volume 67, Issue 2, pp 215–219 | Cite as

Quantitative Evaluations of the Contribution of the Excitatory Ionic Conductance to Repetitive Spiking in a Mathematical Model of Medial Vestibular Nucleus Neurons

  • Takaaki ShirahataEmail author
Short Communication

Abstract

Medial vestibular nucleus neurons show spontaneous repetitive spiking. This spiking activity was reproduced by a Hodgkin–Huxley-type mathematical model, which was developed in a previous study. The present study performed computer simulations of this model to evaluate the contribution of the excitatory ionic conductance to repetitive spiking. The present results revealed the difference in the influence of the transient sodium, persistent sodium, and calcium conductance on spiking activity. The differences between the present and previous results obtained from other neuronal mathematical models were discussed.

Keywords

Medial vestibular nucleus neurons spiking mathematical model sodium conductance calcium conductance 

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Copyright information

© Akadémiai Kiadó, Budapest 2016

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  1. 1.Laboratory of Pharmaceutical Education, Kagawa School of Pharmaceutical SciencesTokushima Bunri UniversitySanuki, KagawaJapan

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