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Characterisation of Mitochondrial Haplotypes Occurred in a Candida Albicans Population

Acta Biologica Hungarica volume 67, pages112–120(2016)Cite this article

Abstract

The genetic background of mitochondrial DNA polymorphism in Candida albicans was studied by physical and functional mapping of four haplotypes identified recently in a hospital-population. The restriction patterns revealed considerable differences; however, the size of the mitochondrial DNA did not vary significantly. Sequence data demonstrated that size differences arose by short deletions, while restriction fragment length polymorphisms are caused by nucleotide substitutions in single sites. Gene rearrangement could not be detected; nevertheless, the coincidence of nucleotide substitution pattern in the inverted repeat region suggested the occurrence of homologue recombination.

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Author information

Affiliations

  1. Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary

    Ilona Pfeiffer, Zoltán Farkas, Judit Kucsera & Csaba Vágvölgyi

  2. Botany and Microbiology Department, King Saud University, Riyadh, Kingdom of Saudi Arabia

    Muthusamy Chandrasekaran, Shine Kadaikunnan, Naiyf S. Alharbi & Csaba Vágvölgyi

Authors
  1. Ilona Pfeiffer
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  2. Zoltán Farkas
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  3. Judit Kucsera
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  4. Muthusamy Chandrasekaran
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  5. Shine Kadaikunnan
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  6. Naiyf S. Alharbi
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  7. Csaba Vágvölgyi
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Corresponding author

Correspondence to Ilona Pfeiffer.

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Pfeiffer, I., Farkas, Z., Kucsera, J. et al. Characterisation of Mitochondrial Haplotypes Occurred in a Candida Albicans Population. BIOLOGIA FUTURA 67, 112–120 (2016). https://doi.org/10.1556/018.67.2016.1.9

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Keywords

  • Candida albicans
  • mitochondrial DNA
  • sequences
  • PCR