Abstract
A one-pot three-component Biginelli-like reaction of enaminones, aldehydes with urea/thiourea in the presence of 2-pyrrolidonium bisulphate as an acidic ionic liquid catalyst for the preparation of 6-unsubstituted dihydropyrimidinones is described. The excellent yield, short reaction time, simple procedure and avoidance of the use of organic solvents are some advantages of this method.
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Alinezhad, H., Tajbakhsh, M., Zare, M. et al. Solvent-free synthesis of 6-unsubstituted dihydropyrimidinones using 2-pyrrolidonium bisulphate as efficient catalyst. Chem. Pap. 70, 1126–1130 (2016). https://doi.org/10.1515/chempap-2016-0048
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DOI: https://doi.org/10.1515/chempap-2016-0048