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Facile and direct synthesis of symmetrical acid anhydrides using a newly prepared powerful and efficient mixed reagent

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Abstract

An efficient mixed reagent for direct synthesis of symmetrical carboxylic anhydrides from carboxylic acids has been prepared. Carboxylic acids are converted to anhydrides using triphenylphosphine/trichloroisocyanuric acid under mild reaction conditions at room temperature. Short reaction time, excellent yields of products, low cost, availability of reagents, simple experimental procedure, and easy work-up of the products are the main advantages of the presented method.

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  1. Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, 9177948974, Mashhad, Iran

    Hamed Rouhi-Saadabad & Batool Akhlaghinia

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  1. Hamed Rouhi-Saadabad
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Rouhi-Saadabad, H., Akhlaghinia, B. Facile and direct synthesis of symmetrical acid anhydrides using a newly prepared powerful and efficient mixed reagent. Chem. Pap. 69, 479–485 (2015). https://doi.org/10.1515/chempap-2015-0042

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