Detection of Dirofilaria immitis antigen and antibodies against Anaplasma phagocytophilum, Borrelia burgdorferi and Ehrlichia canis in dogs from ten provinces of China
Despite the fact vector-borne diseases (VBDs) have been increasingly reported in dogs worldwide, there are only limited reports on VBDs in dogs in China with most being based on molecular detection of active infections. To provide further data on the exposure of dogs in China to VBD agents, we used commercial immunochromatographic assays to test plasma from 637 apparently healthy indoor and breeding colony dogs from 21 veterinary clinics in 10 provinces in China and a commercial dog breeding facility for circulating antigen of Dirofilaria immitis, and for circulating antibodies against Ehrlichia spp., Anaplasmaspp., and Borrelia burgdorferi. Overall, we found only low levels of exposure to Ehrlichia spp. (4.7%; 30/637), Anaplasma spp. (1.4%; 9/637), B. burgdorferi (0.9%; 6/637) and D. immitis (0.2%; 1/637) with most of the positive animals coming from the commercial breeding colony (26/103; 25.2%) where ectoparasites were most commonly noted. At least one vector-borne agent was found in dogs from 6 of the 10 provinces investigated. Our results confirm exposure of dogs from around China to a variety of VBDs, even indoor pets seldom observed to harbor ectoparasites.
KeywordsVector-borne agents SNAP® 4Dx® dogs China
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- Chandrashekar, R., Mainville, C.A., Beall, M.J., O’Connor, T., Eberts M.D., Alleman A.R. et al. 2010. Performance of a commercially available in-clinic ELISA for the detection of antibodies against Anaplasma phagocytophilum, Ehrlichia canis, and Borrelia burgdorferi and Dirofilaria immitis antigen in dogs. American Journal of Veterinary Research, 71, 1443–1145. DOI: 10.2460/ajvr.71.12.1443CrossRefGoogle Scholar
- Ma, D., Ding, X., Cao, J., Xun, X., Cheng Z. 2012. The situation of dog source in China. China Working Dog, 1, 45–50Google Scholar
- Wong, S.S., Teng, J.L., Poon, R.W., Choi, G.K., Chan, K.H., Yeung M.L., et al. 2011. Comparative evaluation of a point-of-care immunochromatographic test SNAP 4Dx with molecular detection tests for vector-borne canine pathogens in Hong Kong. Vector Borne and Zoonotic Diseases, 11, 1269–1277. DOI: 10.1089/vbz.2010.0265CrossRefGoogle Scholar