Journal of Molecular Neuroscience

, Volume 20, Issue 1, pp 1–13 | Cite as

Neural growth hormone

An update
  • Steve Harvey
  • Kerry Hull
Review Article


It is now well established that growth hormone (GH) gene expression is not restricted to the pituitary gland and occurs in many extrapituitary tissues, including the central and peripheral nervous systems. Indeed, GH gene expression occurs in the brain prior to its ontogenic appearance in the pituitary gland, and GH may have evolved phylogenetically as a neuropeptide, rather than as an endocrine. Recent studies on the regulation and roles of neural GH in health and disease are the focus of this brief review.

Index Entries

Growth hormone (GH) GH receptor (GHR) brain spinal cord retina 


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Copyright information

© Humana Press Inc 2003

Authors and Affiliations

  1. 1.Department of PhysiologyUniversity of AlbertaEdmontonCanada
  2. 2.Department of BiologyBishop’s UniversityLennoxvilleCanada

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