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Cecum malakoplakia

A tumor-like lesion with coexistent adenocarcinoma
  • Marina Perdiki
  • Andreas C. Lazaris
  • George E. Theodoropoulos
  • George E. Sofos
  • Panayotis S. Davaris
Case Report
  • 31 Downloads

Abstract

We report the case of a 75-year-old Caucasian male who presented with acute abdomen and fecal leakage from his old appendectomy scar and required exploratory laparotomy. A large cecal mass was found and a right colectomy was performed. At pathology, the neoplastic mass was identified as malakoplakia with a small area corresponding to a moderately differentiated colonic adenocarcinoma.

Occurrence of malakoplakia in the cecum, associated with adenocarcinoma, is extremely rare if we take into account the limited number of the reported cases of its coexistence with colonic cancer; our case is the second report of such an entity in the cecum. The unusual presence of fistula to the appendectomy scar may be related to the infiltrative nature of the histiocytes constituting this process. Immunochemical studies can assist in the histopathologic differentiation of malakoplakia from other entities that might represent with this tumor-like configuration.

Key Words

Malakoplakia colon cancer adenocarcinoma fistula cecal mass 

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References

  1. 1.
    Anderson MD. Dorland’s illustrated medical dictionary, 28th ed. WB Saunders Company, Philadelphia 1994.Google Scholar
  2. 2.
    Mc Clure J. Malakoplakia of the gastrointestinal tract. Postgrad Med J 1981;57:95–103.CrossRefGoogle Scholar
  3. 3.
    Whitehead R, Gastrointestinal and oesophageal pathology, 2nd ed. Churchill Livingstone, Edinburgh, 1999.Google Scholar
  4. 4.
    Fenoglio-Preiser C. Gastrointestinal pathology an atlas and text, 2nd ed. Lippincott-Raven Publishers, Philadelphia 1999.Google Scholar
  5. 5.
    Bates AW, Dev S, Baithun SI. Malakoplakia and colorectal adenocarcinoma. Postgrad Med J 1997;73:171–173.PubMedGoogle Scholar
  6. 6.
    Sandmeier D, Guillou L. Malakoplakia and adenocarcinoma of the cecum: a rare association. J Clin Pathol 1993;46:959–960.PubMedCrossRefGoogle Scholar
  7. 7.
    Rosai J, Ackerman’s Surgical Pathology, 8th ed. Mosby-Year Book Inc., St. Louis 1996.Google Scholar

Copyright information

© Humana Press Inc 2002

Authors and Affiliations

  • Marina Perdiki
    • 2
  • Andreas C. Lazaris
    • 2
  • George E. Theodoropoulos
    • 1
  • George E. Sofos
    • 2
  • Panayotis S. Davaris
    • 2
  1. 1.Diplomat of American Board of SurgeryAthensGreece
  2. 2.Dept of Pathology, School of MedicineAthens UniversityAthensGreece

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