Skip to main content
Log in

Solid pseudopapillary tumor of the pancreas

  • Case Report
  • Published:
International Journal of Pancreatology Aims and scope Submit manuscript

Summary

Background. Its considerable size at the time of diagnosis and low grade of malignancy are typical features of the solid-pseudopapillary tumor, which has a tendency to predominantly affect young females. A relationship to the long-term intake of oral contraceptives is discussed. Invasive tumor growth or metastases have been observed only rarely until now.

Methods. The 53-yr-old female patient we report on here was treated by radical partial pancreatoduo-denectomy for a nonmetastasizing solid-pseudopapillary tumor of the pancreatic head (T1bN0M0) 19 mo ago.

Results. Histopathological studies made a definitive diagnosis of solid-pseudopapillary tumor. The patient is recurrence-free, and there are no signs of metastases at present. Since a microscopically invasive tumor growth is assumed, oncologically curative resection should be preferred vs the less radical enucleation.

Conclusion. In this report, a case of the rare solid-pseudopapillary tumor of the pancreas is described. In contrast to other pancreatic tumors, the semimalignant solid-pseudopapillary tumor has a favorable prognosis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Frantz VK. Tumor of the pancreas. In: Blumberg CW (ed) Atlas of Tumor Pathology, Series 1, Fascicles 27 and 28. Washington, DC: Armed Forces Institute of Pathology, 1959; pp 32, 33.

    Google Scholar 

  2. Klöppel G, Solcia E, Longnecker DS, Capella C, Sobin LH. Histological typing of tumours of the exocrinic pancreas. In: WHO International Classification of Tumours. Springer, Berlin Heidelberg New York, 1996; 8452/1.

    Google Scholar 

  3. Compagno J, Oertel JE, Krezmar M. Solid and papillary neoplasm of the pancreas, probably of small duct origin: A clinocopathologic study of 52 cases. Lab Invest 1979; 40: 248,249.

    Google Scholar 

  4. Cubilla AL, Fitzgerald PJ. Tumors of the exocrine pancreas. In: Hartmann WH, Sobin LH (eds) Atlas of Tumor Pathology, Series 2, Fascicle 19. Washington, DC: Armed Forces Institute of Pathology, 1984; pp 201–207.

    Google Scholar 

  5. Kaufman SL, Reddick RL, Stiegel MD, Wild RE, Thomas CG. Papillary cystic neoplasm of the pancreas: a curable pancreatic tumor. World J Surg 1986; 10: 851–859.

    Article  PubMed  CAS  Google Scholar 

  6. Sanfey H, Mendelsohn G, Cameron JL. Solid and papillary neoplasm of the pancreas. A potentially curable surgical lesion. Ann Surg 1983; 197: 272–275.

    Article  PubMed  CAS  Google Scholar 

  7. Höfler H. Prognosefaktoren beim Pankreascarcinom. Chirurg 1994; 65: 253–257.

    PubMed  Google Scholar 

  8. Klöppel G, Morohoshi T, John HD, Oehmichen W, Opitz K, Angelkort A, et al. Solid and cystic acinar cell tumor of the pancreas: a tumor in young women with favourable prognosis. Virchows Arch A Pathol Anat Histopathol 1981; 392: 171–183.

    Article  Google Scholar 

  9. Learmonth GM, Proce SK, Visser AE, Emms M. Papillary and cystic neoplasm of the pancreas: an acinar cell tumor? Histopathology 1985; 9: 63–79.

    Article  PubMed  CAS  Google Scholar 

  10. Morohoshi T, Held G, Klöppel G. Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases. Histopathology 1983; 7: 665–661.

    Article  Google Scholar 

  11. Rückert K, Klöppel G, Treu HA, Altmeier A, Hempel D, Lingg G. Solid-zystischer Acinuszelltumor des Pankreas. Dtsch Med Wochenschr 1982; 107: 1015–1020.

    Article  PubMed  Google Scholar 

  12. Schlosnagle DC, Campbell WG. The papillary and solid neoplasm of the pancreas. Cancer 1981; 47: 2603–2610.

    Article  PubMed  CAS  Google Scholar 

  13. Yagihashi S, Sato I, Kaimori M, Matsumoto J, Nagai K. Papillary and cystic tumor of the pancreas. Two cases indistinguishable from islet cell tumor. Cancer 1988; 61: 1241–1247.

    Article  PubMed  CAS  Google Scholar 

  14. Mao C, Guvendi M, Domenico DR, Kim K, Thomford NR, Howard JM. Papillary cystic and solid tumors of the pancreas: a pancreatic embryonic tumor? Studies of three cases and cumulative review of the world’s literature. Surgery 1995; 118: 821–828.

    Article  PubMed  CAS  Google Scholar 

  15. Matsunou H, Konishi F. Papillary-cystic neoplasm of the pancreas. A clinicopathologic study concerning the tumor aging and malignancy of nine cases. Cancer 1990; 65: 283–291.

    Article  PubMed  CAS  Google Scholar 

  16. Rustin RB, Broughan TA, Hermann RE, Grundfest-Broniatowski SF, Petras RE, Hart WR. Papillary cystic epithelial neoplasms of the pancreas. A clinical study of four cases. Arch Surg 1986; 121: 1073–1076.

    PubMed  CAS  Google Scholar 

  17. Siech M, Merkle E, Mattfeldt T, Widmaier U, Brambs HJ, Beger HG. Solid-pseudopapilläre Tumoren des Pankreas. Chirurg 1996; 67: 1012–1015.

    Article  PubMed  CAS  Google Scholar 

  18. Tarpila E, Borch K, Franzen L, Andersson R, Evander A, Lasson A, et al. Cystic neoplasms of the pancreas: a clinicopathological study of 38 cases. Dig Surg 1989; 6: 138–141.

    Article  Google Scholar 

  19. Warshaw AL, Compton CC, Lewandrowski K, Cardenosa G, Müller PR. Cystic tumors of the pancreas. New clinical, radiologic and pathologic observations in 67 patients. Ann Surg 1990; 212: 432–443.

    Article  PubMed  CAS  Google Scholar 

  20. Yamaguchi K, Hirakata R, Kitamura K. Papillary cystic neoplasm of the pancreas: radiological and pathological characteristics in 11 cases. Br J Surg 1990; 77: 1000–1003.

    Article  PubMed  CAS  Google Scholar 

  21. Nishihara K, Nagoshi M, Tsuneyoshi M, Yamaguchi K, Hayasshi I. Papillary cystic tumors of the pancreas. Assessment of their malignant potential. Cancer 1993; 71: 82–92.

    Article  PubMed  CAS  Google Scholar 

  22. Ohashi K, Nakajima Y, Hisanaga M, Nakano H, Tsutsumi M, Kondoh S, Konishi Y. A solid and papillary (solid-cystic) tumor of the pancreas occurring in a 36-year-old man: report of case. Surg Today 1993; 23: 551–555.

    Article  PubMed  CAS  Google Scholar 

  23. Ohiwa K, Igarashi M, Nagasue N, Nagasaki M, Harada T. Solid and cystic tumor (SCT) of the pancreas in an adult man. HPB Surg 1997; 10: 315–321.

    Article  PubMed  CAS  Google Scholar 

  24. Wilson MB, Adams DB, Garen PD, Gansler TS. Aspiration cytologic, ultrastructural, and DNA cytometric findings of solid and papillary tumor of the pancreas. Cancer 1992; 69: 2235–2243.

    Article  PubMed  CAS  Google Scholar 

  25. Cappellari JO, Geisinger KR, Albertson KR, Wolfman NT, Kute TE. Malignant papillary cystic tumor of the pancreas. Cancer 1990; 66: 193–198.

    Article  PubMed  CAS  Google Scholar 

  26. Horisawa M, Niinomi N, Sato T, Yokoi S, Oda K, Ichikawa M, Hayakawa S. Frantz’s tumor (solid and cystic tumor of the pancreas) with liver metastasis: successful treatment and long-term follow-up. J Pediatr Surg 1995; 30: 724–726.

    Article  PubMed  CAS  Google Scholar 

  27. Ogawa T, Isaji S, Okamura K, Noguchi T, Mizumoto R, Ishihara A. A case of radical resection for solid cystic tumor of the pancreas with widespread metastases in the liver and greater omentum. J Gastroenterol 1993; 88: 1436–1439.

    CAS  Google Scholar 

  28. Kamei K, Funabiki T, Ochiai M, Amano H, Kasahara M, Sakamoto T. The cases of solid and cystic tumor of the pancreas. Int J Pancreatol 1991; 10: 269–278.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Piatek, S., Manger, T., Röse, I. et al. Solid pseudopapillary tumor of the pancreas. International Journal of Pancreatology 27, 77–81 (2000). https://doi.org/10.1385/IJGC:27:1:77

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1385/IJGC:27:1:77

Key Words

Navigation