Automated DNA profile analysis
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DNA profile analysis is not a simple process. Stringent demands are placed on the accuracy and consistency of forensic evidence so that complex, robust, and reproducible guidelines are necessary to assist the analyst and ensure mistakes are eliminated before a final profile is reported. The guidelines used for forensic DNA profile interpretation are formulated by investigation and statistical evaluation of all aspects of the analytical procedure. All the resulting rules, formulas, and thresholds are perfectly suited to programming of “expert systems”—software programs that imitate the human expert in decision-based processes to formulate a conclusion. Expert systems in forensic DNA analysis will contribute greatly to this field by increasing analytical throughput. The net result of this will be an increase in the human resources available for the research and development of improved methodologies, to ensure that forensic DNA profiling continues to advance at its current impressive rate.
Key WordsForensic science DNA profiling mixture analysis expert systems
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- 1.Howitt T. Maximising the value of DNA evidence through a service approach. Paper presented at the 17th meeting of the International Association of Forensic Sciences, Hong Kong, August, 2005.Google Scholar
- 2.AmpF/STR® SGM Plus™ PCR amplification kit User’s Manual. Applied Biosystems, Foster City, CA, USA. Copyright 2001.Google Scholar
- 8.Werrett D, Pinchin R, Hale R. Problem solving: DNA data acquisition and analysis. Profiles in DNA 1998;2:3–6.Google Scholar