Forensic Science, Medicine, and Pathology

, Volume 1, Issue 4, pp 285–288 | Cite as

Automated DNA profile analysis

DNA Reviews

Abstract

DNA profile analysis is not a simple process. Stringent demands are placed on the accuracy and consistency of forensic evidence so that complex, robust, and reproducible guidelines are necessary to assist the analyst and ensure mistakes are eliminated before a final profile is reported. The guidelines used for forensic DNA profile interpretation are formulated by investigation and statistical evaluation of all aspects of the analytical procedure. All the resulting rules, formulas, and thresholds are perfectly suited to programming of “expert systems”—software programs that imitate the human expert in decision-based processes to formulate a conclusion. Expert systems in forensic DNA analysis will contribute greatly to this field by increasing analytical throughput. The net result of this will be an increase in the human resources available for the research and development of improved methodologies, to ensure that forensic DNA profiling continues to advance at its current impressive rate.

Key Words

Forensic science DNA profiling mixture analysis expert systems 

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Copyright information

© Humana Press Inc 2005

Authors and Affiliations

  1. 1.Forensic Pathology UnitUniversity of LeicesterLeicesterUnited Kingdom

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