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Biological Trace Element Research

, Volume 96, Issue 1–3, pp 255–262 | Cite as

Effects of zinc and melatonin deficiency on testicular tissue of rats

  • Ahmet Oztürk
  • Abdulkerim Kasim Baltaci
  • Cem Seref Bediz
  • Rasim Mogulkoc
  • Salim Güngör
Article

Abstract

The present study was designed to investigate the effects of zinc and/or melatonin deficiency on rat testes. A total of 24 adult male Sprague-Dawley rats were used in this study. The rats were divided into four groups of six rats each, as follows: (I) controls, (II) zinc deficient, (III) pinealectomized, zinc normal, and (IV) pinealectomized, zinc deficient. The plasma zinc levels in the control group were higher than in all the other groups (p<0.01), and those of the zinc-deficient groups II and IV were significantly lower than for group III (p<0.01). The melatonin levels in the controls were also significantly higher than for all other groups (p<0.01) There was no significant difference in sperm production between the controls and the group of animals that had no epiphysis. A significant suppression was observed in the spermatogenetic activity of the zinc-deficient groups (p<0.01). The suppression was higher in group II than in group IV. These results indicate that testicular damage caused by zinc deficiency may be reduced by melatonin deficiency.

Index Entries

Melatonin pinealectomy rats testes zinc deficiency 

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Copyright information

© Humana Press Inc. 2003

Authors and Affiliations

  • Ahmet Oztürk
    • 1
  • Abdulkerim Kasim Baltaci
    • 2
  • Cem Seref Bediz
    • 4
  • Rasim Mogulkoc
    • 2
  • Salim Güngör
    • 3
  1. 1.Department of Urology, Medical SchoolSelcuk UniversityKonyaTurkey
  2. 2.Department of Physiology, Medical SchoolSelcuk UniversityKonyaTurkey
  3. 3.Department of Pathology, Medical SchoolSelcuk UniversityKonyaTurkey
  4. 4.Department of Physiology, Medical SchoolDokuz Eylul UniversityIzmirTurkey

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