Levels of zinc and magnesium in senile and diabetic senile cataractous lenses
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Zinc and magnesium in serum, hair, and lens were determined in diabetic and nondiabetic patients who have been operated because of senile cataract. Both trace elements were measured by atomic absorption spectrometry, after acidic digestion of the lens and hair samples. Although there was no difference in serum, lens, and hair levels of magnesium between the two groups, the lens levels of zinc in diabetic patients (0.56±0.05 µmol/g dry weight) were significantly higher as compared with nondiabetic group (0.42±0.03 µmol/g dry weight). There was no statistically significant difference in serum and hair levels of zinc between the groups. The increased concentration of zinc in the lens of diabetic patients suggests that zinc might play a role in developmental mechanism of the diabetic senile cataract.
Index EntriesDiabetes lens cataract zinc magnesium
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- 2.M. A. Kass, F. G. Berson, L. A. Gans, D. J. Schanzlin, and B. J. Shingleton, The lens, K. A. Hecht, B. Nichols, and J. V. Bueren eds., American Academy of Ophthalmology, San Francisco, CA, Sect. pp. 102–150 (1990–1991).Google Scholar
- 4.J. D. Wilmor and D. F. Foster, Diabetes mellitus, in Williams’ Textbook of Endocrinology, R. H. Unger and D. W. Foster eds., W. B. Saunders, Philadelphia, pp. 505–1994 (1992).Google Scholar
- 11.M. W. Aguilar, J. M. Laborda, M. C. Martinez-Para, et al., Effect of diabetes on the tissular Zn/Cu ratio, J. Trace Elements Med. Biol. 12, 155–158 (1998).Google Scholar
- 13.X. Liu and Y. Zhang, Study on change in zinc concentration for diabetic cataractous lenses in rats by means of XIXA, Hsueh. Pao. 21, 134–136 (1990).Google Scholar
- 16.M. D. Chen, P. Y. Lin, and C. T. Tsau, Selected metals status in patients with noninsulin-dependent diabetes mellitus, Biol. Trace Element Res. 50, 119–124 (1995).Google Scholar
- 17.C. Ruiz, A. Alegria, and R. Barbera, Selenium, zinc and copper in plasma of patients with diabetes mellitus different metabolic control states, J. Trace Elements Med. Biol. 12, 91–95 (1998).Google Scholar
- 18.C. Terres-Martos, A. M. Navarro, and L. F. Martin, Serum zinc and copper concentrations and Cu-Zn ratios in patients with hepatopathies or diabetes, J. Trace Elements Med. Biol. 12, 44–49 (1998).Google Scholar