Biological Trace Element Research

, Volume 84, Issue 1–3, pp 93–101 | Cite as

The effects of dietary chromium supplementation on some blood parameters in sheep

  • Fatma Uyanik
Article

Abstract

The effects of dietary inorganic chromium on some biochemical parameters were determined in lambs fed either a control diet or a 200-ppb or 400-ppb chromium-supplemented diet. The live weight of the animals were measured and jugular blood samples were collected prior to supplementation (d 0) and on d 20, 40, and 55. On d 55, three animals from each group were slaughtered to measure subcutaneous fat. Sera were analyzed for glucose, triglyceride, total cholesterol, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, total protein, albumin, ALT, AST, and GGT levels. Chromium supplementation had no significant effect on live weight, but subcutaneous fat was reduced significantly in both chromium groups. There was a slight decrease in glucose concentrations in the 200-ppb chromium group, although only the differences on d 55 were significant. Triglyceride levels in both chromium groups were lower than the control group with marked differences in the 400-ppb chromium group. HDL cholesterol levels increased in both treatment groups compare to control, although the differences in the 400-ppb chromium group on d 40 were significant. Serum Cr concentrations slightly but not significantly increased in both chromium groups. No significant differences were found in total and LDL cholesterol, total protein, albumin, ALT, AST, and GGT levels. In conclusion, chromium supplementation may affect carbohydrate and lipid metabolisms and lipid deposition in lambs.

Index Entries

Chromium sheep serum lipids glucose proteins enzymes 

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References

  1. 1.
    W. Mertz, Chromium occurrence and function in biological system, Am. Physiol. Soc. 49, 163–239 (1969).Google Scholar
  2. 2.
    L. R. McDowell, Minerals in Animal and Human Nutrition, Academic, London (1992).Google Scholar
  3. 3.
    R. A. Anderson, Effects of chromium on body composition and weight loss, Nutr. Rev. 56, 266–270 (1998).PubMedCrossRefGoogle Scholar
  4. 4.
    E. B. Kegley, J. W. Spears, and J. H. Eisemann, Performance and glucose metabolism in calves fed a chromium-nicotinic acid complex or chromium chloride, J. Dairy Sci. 80, 1744–1750 (1997).PubMedGoogle Scholar
  5. 5.
    S. Moonsie-Shageer and D. N. Mowat, Effect of supplemental chromium on performance, serum constituents, and immune status of stressed feeder calves, J. Anim. Sci. 71, 231–238 (1993).Google Scholar
  6. 6.
    E. T. Kornegay, Z. Wang, C. M. Wood, and M. D. Lindemann, Supplemental chromium picolinate influences nitrogen balance, dry matter digestibility, and carcass traits in growing-finishing pigs, J. Anim. Sci. 75, 1319–1323 (1997).PubMedGoogle Scholar
  7. 7.
    K. W. Mooney and G. L. Cromwell, Efficacy of chromium picolinate and chromium chloride as potential carcass modifiers in swine, J. Anim. Sci. 75, 2661–2671 (1997).PubMedGoogle Scholar
  8. 8.
    L. Kitchalong, J. M. Fernandez, L. D. Bunting, A. M. Chapa, L. S. Sticker, E. K. Amoikon, et al., Chromium picolinate supplementation in lamb rations: effects on performance, nitrogen balance, endocrine and metabolic parameters, J. Anim. Sci. 71, 291 (1993) (abstract).Google Scholar
  9. 9.
    L. Kitchalong, J. M. Fernandez, L. D. Bunting, L. L. Southern, and T. D. Bidner, Influence of chromium tripicolinate on glucose metabolism and nutrient partitioning in growing lambs, J. Anim. Sci. 73, 2694–2705 (1995).PubMedGoogle Scholar
  10. 10.
    L. J. Samsell and J. W. Spears, Chromium supplementation effects on blood constituents in lambs fed high or low fiber diets, Nutr. Res. 9, 889–899 (1989).CrossRefGoogle Scholar
  11. 11.
    H. Demir, Farkli beslenme düzeyleri ile besiye alinan 5–7 aylik Kivircik erkek kuzularin besi ve karkas özellikleri, Istanbul Üniv. Vet. Fak. Derg. 21, 117–130 (1995).Google Scholar
  12. 12.
    Perkin-Elmer, Analytical Methods for the Atomic Absorption Spectrophotometry, Perkin-Elmer, Norwalk, CT (1982).Google Scholar
  13. 13.
    S. L. Boleman, S. J. Boleman, T. D. Bidner, L. L. Southern, T. L. Ward, J. E. Pontif, et al., Effect of chromium picolinate on growth, body composition, and tissue accretion in pigs, J. Anim. Sci. 73, 2033–2042 (1995).PubMedGoogle Scholar
  14. 14.
    H. Sano, D. N. Mowat, R. O. Ball, and D. R. Trout, Effect of supplemental chromium on whole-body kinetics of glucose, lactate, and propionate in rams fed a high grain diet, Comp. Biochem. Physiol. B Biochem. Mol. Biol. 118, 117–121 (1997).PubMedCrossRefGoogle Scholar
  15. 15.
    T. L. Ward, L. L. Southern, and T. D. Bidner, Interactive effects of dietary chromium trpicolinate and crude protein level in growing-finishing pigs provided inadequate and adequate pen space, J. Anim. Sci. 75, 1001–1008 (1997).PubMedGoogle Scholar
  16. 16.
    S. Sasaki, Mechanism of insulin resistance in the post receptor events in sheep: 3-O-methylglucose transport in ovine adipocytes, Horm. Metab. Res. 22, 457–461 (1990).PubMedCrossRefGoogle Scholar
  17. 17.
    E. G. Offenbacher and F. X. Pi-Sunyer, Chromium in human nutrition, Annu. Rev. Nutr. 8, 543–563 (1988).PubMedCrossRefGoogle Scholar
  18. 18.
    T. E. Broad, J. R. Sedcole, and A. S. Ngan, Incorporation of glucose into lipid of perirenal and subcutaneous adipocytes of rats and sheep: influence of insulin, Aust. J. Biol. Sci. 36, 147–156.Google Scholar
  19. 19.
    R. G. Lefavi, G. D. Wilson, R. E. Keith, R. A. Anderson, D. L. Blessing, C. G. Hames, et al., Lipid lowering effect of a dietary chromium (III)-nicotinic acid complex in male athletes, Nutr. Res. 13, 239–249 (1993).CrossRefGoogle Scholar
  20. 20.
    A. Subiyatno, D. N. Mowat, and W. Z. Yang, Metabolite and hormonal response to glucose or propionate infusion in periparturient dairy cows supplemented with chromium, J. Dairy Sci. 79, 1436–1445 (1996).PubMedCrossRefGoogle Scholar
  21. 21.
    R. I. Press, J. Geller, and G. W. Evans, The effects of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects, West. J. Med. 152, 41–45 (1990).PubMedGoogle Scholar
  22. 22.
    T. G. Page, L. L. Southern, T. L. Ward, and D. L. Thompson, Jr., Effects of chromium picolinate on growth and serum and carcass traits of growing-finishing pigs, J. Anim. Sci. 71, 656–662 (1993).PubMedGoogle Scholar
  23. 23.
    E. K. Amoikon, J. M. Fernandez, L. L. Southern, D. L. Thompson, Jr., T. L. Ward, and B. M. Olcott, Effects of chromium tripicolinate on growth, glucose tolerance, insulin sensitivity, plasma metabolites, and growth hormone in pigs, J. Anim. Sci. 73, 1123–1130 (1995).PubMedGoogle Scholar
  24. 24.
    R. A. Anderson, M. M. Polansky, N. A. Bryden, E. E. Roginski, W. Mertz, and W. Glinsmann, Chromium supplementation of human subjects: effects on glucose, insulin, and lipid variables, Metabolism 32, 894–899 (1983).PubMedCrossRefGoogle Scholar
  25. 25.
    A. Altintaş, and U. R. Fidanci, Evcil hayvanlarda ve insanda kanin biyokimyasal normal değerleri, Ankara Üniv. Vet. Fak. Derg. 40, 173–186 (1993).Google Scholar

Copyright information

© Humana Press Inc. 2001

Authors and Affiliations

  • Fatma Uyanik
    • 1
  1. 1.Biochemistry Department, Faculty of Veterinary MedicineUniversity of ErciyesKayseriTurkey

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