Biological Trace Element Research

, Volume 101, Issue 2, pp 133–145 | Cite as

Compositional changes of the muscular layers of the stomach with aging

  • Cho Azuma
  • Yoshiyuki Tohno
  • Setsuko Tohno
  • Yumi Moriwake
  • Masako Utsumi
  • Takeshi Minami
  • Toshio Imada
Original Articles
  • 42 Downloads

Abstract

To elucidate compositional changes of the stomach with aging, the authors investigated age-related changes of the elements and relationships among the elements in the muscular layers of the pylorus, cardia, lesser curvature, and greater curvature by inductively coupled plasma-atomic emission spectrometry. After ordinary dissection by medical students, the pylori, cardias, lesser curvatures, and greater curvatures were removed from the subjects, consisting of 19 men and 1 woman, ranging in age from 65 to 95 yr. The muscular layers were isolated and the element contents were determined.

The calcium content increased progressively with aging in the muscular layers of the pylorus, cardia, and lesser curvature, whereas it tended to increase in the muscular layer of the greater curvature with aging. Regarding sulfur, the content increased significantly in the muscular layer of the pylorus with aging, but not significantly in the muscular layers of the cardia, lesser curvature, and greater curvature with aging.

Regarding the relationships among the elements, significant direct correlations were found among calcium, phosphorus, sulfur, and magnesium in both the muscular layers of the pylori and cardias, with some exceptions.

Index Entries

Stomach pylorus cardia smooth muscle calcium aging 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Y. Tohno, S. Tohno, T. Minami, et al., Age-related changes of mineral contents in the human thoracic aorta and in the cerebral artery. Biol. Trace Element Res. 54, 23–31 (1996).Google Scholar
  2. 2.
    S. Tohno and Y. Tohno, Age-related differences in calcium accumulation in human arteries. Cell. Mol. Biol. 44, 1253–1263 (1998).PubMedGoogle Scholar
  3. 3.
    S. Tohno, M. Masuda, Y Tohno, et al., High accumulation of calcium and phosphorus in human iliac arteries. Biol. Trace Element Res. 70, 41–49 (1999).Google Scholar
  4. 4.
    S. Tohno, Y. Tohno, T. Minami, et al., A high accumulation of minerals in human internal jugular vein, Biol. Trace Element Res. 62, 17–23 (1998).Google Scholar
  5. 5.
    Y. Tohno, S. Tohno, C. Azuma, et al., Age-related changes of elements in human thoracic ducts and azygos veins and relationships among elements, Biol. Trace Element Res. 96, 93–107 (2003).CrossRefGoogle Scholar
  6. 6.
    Y. Tohno, S. Tohno, T. Minami, et al., Differences in accumulation of elements in human cardiac valves. Biol. Trace Element Res. 77, 107–118 (2000).CrossRefGoogle Scholar
  7. 7.
    S. Tohno, Y. Tohno, T. Minami, et al., Difference of mineral contents in human intervertebral disks and its age-related change, Biol. Trace Element Res. 52, 117–124 (1996).Google Scholar
  8. 8.
    Y. Tohno, M. Utsumi, S. Tohno, et al., A constancy of mineral contents in human auditory ossicles, Acta Anat. Nippon. 72, 531–534 (1997).PubMedGoogle Scholar
  9. 9.
    Y. Tohno, Y. Takano, S. Tohno, et al., Age-related variations of elements as compared among optic, radial, and sciatic nerves, Biol. Trace Element Res. 77, 119–129 (2000).CrossRefGoogle Scholar
  10. 10.
    Y. Tohno, Y. Takano, S. Tohno, et al., Age-dependent decreases of phosphorus and magnesium in human Achilles’ tendons, Biol. Trace Element Res. 74, 1–9 (2000).CrossRefGoogle Scholar
  11. 11.
    Y. Tohno, Y. Moriwake, Y. Takano, et al., Age-related changes of elements in human anterior cruciate ligaments and ligamenta capitum femorum, Biol. Trace Element Res. 68, 181–192 (1999).Google Scholar
  12. 12.
    Y. Takano, Y. Tohno, Y. Moriwake, et al., Age-related changes of elements in human ureter, Biol. Trace Element Res. 74, 117–125 (2000).CrossRefGoogle Scholar
  13. 13.
    S. Yoshida, Y. Takano, Y. Moriwake, et al., Increases of calcium and magnesium and decreases of phosphorus and iron with aging in human uterine tubes, Biol. Trace Element Res. 80, 13–22 (2001).CrossRefGoogle Scholar
  14. 14.
    J. G. Moore, C. Tweedy, P. E. Christian, et al., Effect of age on gastric emtyping of liquid solid meals in man, Dig. Dis. Sci. 28, 340–344 (1983).PubMedCrossRefGoogle Scholar
  15. 15.
    M. A. Evans, E. J. Triggs, M. Cheung, et al., Gastric emptying rate in the elderly implication for the drug therapy. J. Am. Geriat. Soc. 29, 201–205 (1981).PubMedGoogle Scholar
  16. 16.
    Y. Tohno, S. Tohno, H. Matsumoto, et al., A trial of introducing soft X-ray apparatus into dissection practice for students, J. Nara Med. Assoc. 36, 365–370 (1985) (in Japanese).Google Scholar
  17. 17.
    Y. Tohno, S. Tohno, Y. Moriwake, et al., Accumulation of calcium and phosphorus accompanied by increase of magnesium and decrease of sulfur in human arteries, Biol. Trace Element Res. 82, 9–19 (2001).CrossRefGoogle Scholar
  18. 18.
    Y. Tohno, S. Tohno, Y. Moriwake, et al., Simultaneous accumulation of calcium, phosphorus, and magnesium in various human arteries, Biol. Trace Element Res. 82, 21–28 (2001).CrossRefGoogle Scholar
  19. 19.
    Y. Moriwake, Y. Tohno, S. Tohno, et al., Relationships among element contents in the intimal, middle, and external tunicae of the thoracic aorta, Biol. Trace Element Res. 83, 121–132 (2001).CrossRefGoogle Scholar
  20. 20.
    S. Tohno, Y. Tohno, T. Minami, et al. Relationships among element contents in the internal jugular vein similar to the arteries, Biol. Trace Element Res 88, 223–233 (2002).CrossRefGoogle Scholar
  21. 21.
    Y. Tohno, S. Tohno, H. Satoh, et al., Compositional changes of human mitral valves with aging, Biol. Trace Element Res. 88, 203–213 (2002).CrossRefGoogle Scholar

Copyright information

© Humana Press Inc 2004

Authors and Affiliations

  • Cho Azuma
    • 1
  • Yoshiyuki Tohno
    • 1
  • Setsuko Tohno
    • 1
  • Yumi Moriwake
    • 1
  • Masako Utsumi
    • 1
  • Takeshi Minami
    • 2
  • Toshio Imada
    • 3
  1. 1.Laboratory of Cell Biology, Department of AnatomyNara Medical University, KashiharaNaraJapan
  2. 2.Laboratory of Environmental Biology, Department of Life Science, Faculty of Science and EngineeringKinki UniversityOsakaJapan
  3. 3.First Department of Surgery, Faculty of MedicineYokohama City UniversityYokohama, KanagawaJapan

Personalised recommendations