Abstract
To elucidate compositional changes of arteries with aging, the authors previously investigated age-related changes of mineral contents in the various arteries of Japanese and Japanese monkey. To examine whether there were differences between races in regard to age-related changes of mineral contents and the relationships among element contents in the arteries, the authors investigated the arteries of Thai. The subjects consisted of 13 men and 3 women, ranging in age from 39 to 84 yr. After the ordinary dissection at Chiang Mai University was finished, abdominal aortas, common iliac, internal iliac, and external iliac arteries were resected and the element contents were determined by inductively coupled plasma-atomic emission spectrometry. The contents of calcium, phosphorus, and magnesium became the highest in the fifties in the abdominal aorta, common iliac, and external iliac arteries, whereas the contents of calcium and magnesium became the highest in the sixties in the internal iliac artery, and decreased thereafter. In regard to relationships among element contents, it was found that there were high correlations between calcium and phosphorus contents, between calcium and magnesium contents, and between phosphorus and magnesium in all of the abdominal aortas and three iliac arteries. The mass ratios of magnesium to calcium and phosphorus were each similar in the abdominal aorta, common iliac, and internal iliac arteries, except for the external iliac artery, in which it was slightly high. These revealed that as calcium and phosphorus increased in the arteries with aging, magnesium increased in the arteries as well. The differences between the arteries of Thai and Japanese were discussed in the present article.
Similar content being viewed by others
References
Y. Tohno, S. Tohno, T. Minami, M. Ichii, Y. Okazaki, M. Utsumi, et al., Age-related changes of mineral contents in the human thoracic aorta and in the cerebral artery, Biol. Trace Element Res. 54, 23–31 (1996).
T. Araki and Y. Tohno, Age dependency of nanosecond fluorescence characteristics in human arteries, Front. Med. Biol. Eng. 7, 265–273 (1996).
S. Tohno, Y. Tohno, T. Minami, Y. Okazaki, M. Utsumi, F. Nishiwaki, et al., High accumulation of elements in the human femoral artery, Biol. Trace Element Res. 57, 27–37 (1997).
S. Tohno, Y. Tohno, T. Minami, Y. Okazaki, M. Utsumi, F. Nishiwaki, et al., Differential accumulation of calcium and phosphorus in aged human arteries, Acta Anat. Nippon. 72, 451–454 (1997).
S. Tohno, Y. Tohno, T. Minami, Y. Moriwake, M. Utsumi, F. Nishiwaki, et al., High accumulation of minerals in the human arteries of lower limb, Biol. Trace Element Res. 63, 177–183 (1998).
Y. Tohno, S. Tohno, T. Minami, M. Utsumi, Y. Moriwake, F. Nishiwaki, et al., Age-related changes of mineral contents in the human aorta and internal thoracic artery, Biol. Trace Element Res. 61, 219–226 (1998).
S. Tohno and Y. Tohno, Age-related differences in calcium accumulation in human arteries, Cell. Mol. Biol. 44, 1253–1263 (1998).
S. Tohno, M. Masuda, Y. Tohno, Y. Moriwake, T. Minami, M. Utsumi, et al., High accumulation of calcium and phosphorus in human iliac arteries, Biol. Trace Element Res. 70, 41–49 (1999).
Y. Tohno, S. Tohno, Y. Tateyama, Y. Kida, T. Yasui, M. Hashimoto, et al., Visual demonstration of calcium accumulation in human arteries of upper and lower limbs, Biol. Trace Element Res., 81, 115–125 (2001).
S. Tohno, Y. Tohno, T. Minami, Y. Moriwake, F. Nishiwaki, M. Utsumi, et al., Calcium and phosphorus in aged human cerebral arteries, Biol. Trace Element Res., 81, 105–113 (2001).
Y. Tohno, S. Tohno, Y. Moriwake, C. Azuma, Y. Ohnishi, and T. Minami, Accumulation of calcium and phosphorus accompanied by increase of magnesium and decrease of sulfur in human arteries, Biol. Trace Element Res., in press.
Y. Tohno, S. Tohno, Y. Moriwake, C. Azuma, Y. Ohnishi, and T. Minami, Simultaneous accumulation of calcium, phosphorus, and magnesium in human various arteries, Biol. Trace Element Res., in press.
Y. Moriwake, Y. Tohno, S. Tohno, C. Azuma, and T. Minami, Relationships among element contents in the intimal, middle, and external tunicae of the thoracic aorta, Biol. Trace Element Res., in press.
S. Tohno, Y. Tohno, M. Hayashi, Y. Moriwake, T. Minami, F. Nishiwaki, et al., Accumulation of calcium in the arteries of Japanese monkey, Biol. Trace Element Res., in press.
S. Tohno, Y. Tohno, M. Hayashi, Y. Moriwake, and T. Minami, Accumulation of magnesium as well as calcium and phosphorus in Japanese monkey arteries with aging, Biol. Trace Element Res., in press.
S. Tohno, Y. Tohno, T. Minami, Y. Moriwake, F. Nishiwaki, M. Utsumi, et al., Accumulation of calcium and phosphorus in the mitral valve in comparison with the abdominal aorta and the scaphoid bone, Biol. Trace Element Res. 77, 33–42 (2000).
S. Y. Yu and H. T. Blumenthal, The calcification of elastic fibers. I. Biochemical studies, J. Gerontol. 18, 119–126 (1993).
B. T. Altura, M. Brust, S. Bloom, R. L. Barbour, J. G. Stempak, and B. M. Altura, Magnesium dietary intake modulates blood lipid levels and atherogenesis, Proc. Natl. Acad. Sci. USA 87, 1840–1844 (1990).
B. M. Altura and B. T. Altura, New perspectives on the role of magnesium in the pathophysiology of the cardiovascular system. I. Clinical aspects, Magnesium 4, 226–244 (1985).
M. Hayashi, T. Osakabe, F. Ushio, and Y. Seyama, Qualitative change in the elastin from the calcified portion of human artery, Jpn. J. Geriat. 36, 404–407 (1999) (in Japanese).
S. Tohno, Y. Tohno, M. Masuda, T. Minami, Y. Moriwake, M. Utsumi, et al., A possible balance of magnesium accumulations among bone, cartilage, artery, and vein in single human individuals, Biol. Trace Element Res. 70, 233–241 (1999).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tohno, Y., Tohno, S., Mahakkanukrauh, P. et al. Simultaneous accumulation of magnesium with calcium and phosphorus in aorta and iliac arteries of thai. Biol Trace Elem Res 84, 19–35 (2001). https://doi.org/10.1385/BTER:84:1-3:019
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1385/BTER:84:1-3:019