Annals of Ophthalmology

, Volume 38, Issue 1, pp 43–48 | Cite as

The histopathological effect of intracameral ropivacaine in different concentrations on corneal endothelium

  • Íhsan Çaça
  • Vatan Kavak
  • Kaan Ünlü
  • Seyhmus Ari
  • Yusuf Nergis
  • Gülnür Take
Original Article
  • 8 Downloads

Abstract

We evaluated the histopathological changes occurring in corneal endothelium after intracameral injection ropivacaine into rats. Intracamerally administered ropivacaine in 1, 0.5, and 0.1% concentrations resulted in impairment of hexagonal structure of corneal endothelial cells and inter-cellular junctions, destruction of microvilli on the cell surface, roughness of cell borders, picnotic nucleus, diffuse vacuolization, and crystalysis in mitochondria.

Keywords

Bupivacaine Ropivacaine Intercellular Junction Corneal Endothelium Corneal Endothelial Cell 

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Copyright information

© Humana Press Inc. 2006

Authors and Affiliations

  • Íhsan Çaça
    • 1
  • Vatan Kavak
    • 1
  • Kaan Ünlü
    • 2
  • Seyhmus Ari
    • 3
  • Yusuf Nergis
    • 4
  • Gülnür Take
    • 5
  1. 1.Department of OphthalmologyDicle University Faculty of MedicineDiyarbakirTurkey
  2. 2.Department of OphthalmologyDicle University Faculty of MedicineDiyarbakirTurkey
  3. 3.Department of OphthalmologyDicle University Faculty of MedicineDiyarbakirTurkey
  4. 4.Department of Histology and EmbryologyDicle University Faculty of MedicineDiyarbakirTurkey
  5. 5.Department of Histology and EmbryologyGazi University Faculty of MedicineDiyarbakirTurkey

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