Annals of Ophthalmology

, Volume 37, Issue 2, pp 99–104 | Cite as

Exuberant pigmented conjunctivitis epidemiology, immunology, histopathology, and treatment with mitomycin-C

  • Vania García de Barragan
  • Gonzalo Murillo
  • Pedro de Alarcón
  • Ximena Arze
  • Martin Sangueza
Original Article


We describe a unique form of ocular disease called “exuberant pigmented conjunctivitis” and demonstrate the allergic response to environmental particles combined with high altitude, dust, concentrated ultraviolet rays, and extreme dryness. A nonsteroid treatment with mitomycin-C was studied to avoid known topical steroid side effects.


Astigmatism Ketotifen Pterygium Keratoconus Conjunctival Hyperemia 
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  1. 1.
    Valencia M. Conjunctivits proliferante pigmentada. Hospital Metodista. Trabajo de ingreso a la Sociedad Boliviana de Oftalmología. 1989.Google Scholar
  2. 2.
    Aracena T. Conjunctivitis exuberante pigmentada. Palestra Panamericana Oftalmologica 1977;1:1–20.Google Scholar
  3. 3.
    Parra P, Pagano PB, Tessori S. Conjunctivitis exuberante pigmentada en Prurigo Solar. Rev Argent Dermatol. 1982;62:249–252.Google Scholar
  4. 4.
    Valda Rodríguez L, Aracena T, Sangueza P. Actinoreticulosis y conjunctivitis exuberante pigmetaria. Reporte de un caso. Med-Cutan-Ibero-Lat-Am. 1985;13:511–516.PubMedGoogle Scholar
  5. 5.
    Martinez EC. Incidencia de queratoconjunctivitis exuberante pigmentada en la cirdad de Potosi. Revista: Centro de Investigación Oftalmologica 1993;1:34–35.Google Scholar
  6. 6.
    Murillo G. Niveles de Inmunoglobulia E. en lagrimas de pacientes con conjunctivitis exuberante pigmetada. Trabajo de ingreso a la Sociedad Boliviana de Oftalmología. 1985.Google Scholar
  7. 7.
    Frucht-Perry J, Roxenman Y. The use of low-dose Mitomycin-C for prevention of recurrent pterygium. Ophthalmology 1994;101:759–762.Google Scholar
  8. 8.
    Rossental G, Shokanm A, Lifshitzz T, et al. The use of mitomycin in pterygium surgery. Ann Ophthalmol. 1993;25:427–428.Google Scholar
  9. 9.
    Karamursel E, Hilkmet H, Ge W, et al. A randomized trial of low-dose, topical Mitomycin-C in the treatment of severe vernal keratoconjunctivitis. Ophthalmology 2000;107:263–269.CrossRefGoogle Scholar
  10. 10.
    Dunn JP, Seamone CD, Ostler HB, et al. Development of scleral ulceration and calcification after pterygium excision and mitomycin therapy. Am J Ophthalmol. 1991;112:343–344.PubMedGoogle Scholar
  11. 11.
    Abiose A, Merz M. Cryosurgery in the management of vernal keratoconjunctivitis. Ann Ophthalmol. 1983;15:744–747.PubMedGoogle Scholar

Copyright information

© Humana Press Inc. 2005

Authors and Affiliations

  • Vania García de Barragan
    • 1
  • Gonzalo Murillo
    • 1
  • Pedro de Alarcón
    • 1
  • Ximena Arze
    • 1
  • Martin Sangueza
    • 1
  1. 1.National Institute of Ophthalmology in La PazLa PazBolivia

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