Optimization of L-Lactic acid production from glucose by Rhizopus oryzae ATCC 52311
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The effect of nutrients on L(+)-lactic acid production from glucose was investigated using Rhizopus oryzae ATCC 523 11. From the shake-flask experiments, the optimal medium composition was defined for improved lactic-acid production. In order to enhance lactic-acid production rate and product yield, controlled aeration in a bubble column was conducted under optimal conditions. Results showed a maximum lactic-acid production rate of 2.58 g/L/h was obtained with an initial glucose concentration of 94 g/L. Finallactic-acid concentration of 83 g/L was achieved after 32 h of fermentation with a weight of 0.88 glactic acid/g glucose consumed.
Index EntriesBubble column lactic acid Rhizopus oryzae
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- 1.Tsai, S. P., Coleman, R. D., Moon, S. H., Schneider, K. A., and Millard, C. S. (1993), Appl. Biochem. Biotechnol. 39/40, 323–335.Google Scholar
- 5.Yang, C. W., Lu, Z., and Tsao, G. T. (1995), Appl. Biochem. Biotechnol. 51, 57–71.Google Scholar
- 6.Lin, J., Chen, B., Wu, J., and Cen, P. (1997), Chinese J. Chem. Eng. 5, 49–55.Google Scholar
- 7.Du, J., Cao, N., Gong, C. S., and Tsao, G. T. (1998), Appl. Biochem. Biotechnol. 70/72, 323–329.Google Scholar