Applied Biochemistry and Biotechnology

, Volume 134, Issue 2, pp 165–178 | Cite as

Establishing mathematical and physical models for the adsorption of biomacromolecules

  • Songjun Li
  • Pingchu Chen
  • Wuke Li
  • Xiao Hao
  • Guangfu Yang
Original Research Articles


In this article, a series of mathematical and physical models for the adsorption of biomacromolecules are established. As shown, the adsorption of biomacromolecules is actually considerably complicated and often involves various interactions, such as electrostatic, hydrophobic and hydrogen-bonding, etc. Considering this, these models show that if these interactions are heavily involved in the process, the plot of in Q (or Q) vs In C* is normally expected to be a straight-line. Otherwise, if the linearity exists between C*/Q vs C*, the adsorption would be an ideal process without the intervention of them. Meanwhile, this article also presents corresponding relationships for the adsorption in multisited binding and multilayer forms. Other aspects including ion-exchange systems are also discussed (C*, the equilibrium concentration of biomacromolecules; Q, the adsorbance).

Index Entries

Biomacromolecule adsorption theory interaction ionexchange 


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Copyright information

© Humana Press Inc 2006

Authors and Affiliations

  • Songjun Li
    • 1
  • Pingchu Chen
    • 1
  • Wuke Li
    • 1
  • Xiao Hao
    • 1
  • Guangfu Yang
    • 1
  1. 1.Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of ChemistryCentral China Normal UniversityWuhanP. R. China

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