Applied Biochemistry and Biotechnology

, Volume 134, Issue 2, pp 165–178 | Cite as

Establishing mathematical and physical models for the adsorption of biomacromolecules

  • Songjun Li
  • Pingchu Chen
  • Wuke Li
  • Xiao Hao
  • Guangfu Yang
Original Research Articles

Abstract

In this article, a series of mathematical and physical models for the adsorption of biomacromolecules are established. As shown, the adsorption of biomacromolecules is actually considerably complicated and often involves various interactions, such as electrostatic, hydrophobic and hydrogen-bonding, etc. Considering this, these models show that if these interactions are heavily involved in the process, the plot of in Q (or Q) vs In C* is normally expected to be a straight-line. Otherwise, if the linearity exists between C*/Q vs C*, the adsorption would be an ideal process without the intervention of them. Meanwhile, this article also presents corresponding relationships for the adsorption in multisited binding and multilayer forms. Other aspects including ion-exchange systems are also discussed (C*, the equilibrium concentration of biomacromolecules; Q, the adsorbance).

Index Entries

Biomacromolecule adsorption theory interaction ionexchange 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Butler, J. E. (2000), Methods 22(1), 4–23.CrossRefGoogle Scholar
  2. 2.
    Brahim, S., Narinesingh, D., and Guiseppi-Elie, A. (2002), J. Mol. Catal. B. 18(3), 69–80.CrossRefGoogle Scholar
  3. 3.
    Panphilov, A. S. and Bekish, O. J. L. (1997), Immunol. Lett. 56(2), 462.Google Scholar
  4. 4.
    Glen, S. K., You, H. B., Harry, C., Jan, F. J., and Sung, W. K. (1992), J. Contr. Release 22(2), 83–93.CrossRefGoogle Scholar
  5. 5.
    Norman, E., Williams, P., and Illum, L. (1993), Biomaterials 14(3), 193–202.CrossRefGoogle Scholar
  6. 6.
    Lu, H. B., Homola, J. I., Campbell, C. T., Nenninger, G. G., Yee, S. S., and Ratner, B. D. (2001), Sens, Actuator B. 74(3), 91–99.CrossRefGoogle Scholar
  7. 7.
    Gessner, A., Paulke, B., and Müller, R. H. (2000), Electrophoresis 21(12), 2438–2442.CrossRefGoogle Scholar
  8. 8.
    Haynes, C. A., Sliwinsky, E., and Norde, W. (1994), J. Colloid Interf. Sci. 164(2), 263–514.CrossRefGoogle Scholar
  9. 9.
    Chatterjee, A., Ebina, T., and Iwasaki, T. (2001), Phys. Chem. A. 105(47), 10,694–10,701.CrossRefGoogle Scholar
  10. 10.
    Pei, R., Cui, X., Yang, X., and Iwasaki, T. (2001), Biomacromolecules 2 (2), 463–468.CrossRefGoogle Scholar
  11. 11.
    Yang, C. H. (1998), J. Colloid Interf. Sci. 208(2), 379–387.CrossRefGoogle Scholar
  12. 12.
    Zhou, D., Liu, X, Kaczmarski, K., Felinger, A., and Guiochon, G. (2003), Biotechnol. Prog. 19(3), 945–954.CrossRefGoogle Scholar
  13. 13.
    Calonder, C. and Van Tassel, P. R. (2001), Langmuir 17(14), 4392–4395.CrossRefGoogle Scholar
  14. 14.
    Van Tassel, P. R. (2003), Materialwissenschaft und Werkstofftechnik 34(12), 1129–1132.CrossRefGoogle Scholar
  15. 15.
    Gettens, R. T. T., Bai, Z. J., and Gilbert, J. L. (2005), J. Biomed. Mater. Res. A 72 (3), 246–257.Google Scholar
  16. 16.
    Sharma, S. and Agarwal, G. P. (2002), Adsorption 8(3), 203–213.CrossRefGoogle Scholar
  17. 17.
    Li, Z. J. (1990), in Kinetic Basis For Heterogeneous Catalysis (Li, Z. J., ed.), Beijing Univ. Press, Beijing, China, pp. 39–42.Google Scholar
  18. 18.
    Jiling University (1980), in Basis of Catalysis Action (Jiling Univ., ed.), Chin. Sci. Press, Beijing, China, pp. 1–30.Google Scholar
  19. 19.
    Wassell, D. H. T., Hall, R. H., and Embery, G. (1995), Biomaterials 16(9), 697–702.CrossRefGoogle Scholar
  20. 20.
    Li, R. S., Zhen, K.J., and Wang, G. J (1990), in Basis of Catalysis Action (Li, R. S., Zhen, K. J., and Wang, G. J., eds.), Chin. Sci. Press, Beijing, China, pp. 20–49.Google Scholar
  21. 21.
    Fu, X. C., Shen, W. X., and Yao, T. Y. (1998), in Physicochemistry (Fu, X. C., Shen, W. X., and Yao, T. Y., eds.) Chin. Higher Edu. Press, Beijing, China, pp. 937–942.Google Scholar
  22. 22.
    Li, S. J., Hu, J., and Liu, B. L. (2004), Method Findings Exper. Clin. Pharmacol. 26 (7), 507–513.CrossRefGoogle Scholar
  23. 23.
    Li, S. J., Hu, J., Liu, B. L. (2005), J. Chem. Technol. Biotechnol. 80(5), 531–536.CrossRefGoogle Scholar
  24. 24.
    Ziegler, A., Li-Blatter, X., Seelig, A., and Seelig, J. (2003), Biochemistry 42(30), 9185–9194.CrossRefGoogle Scholar
  25. 25.
    Todd, R. J., Johnson, R. D., and Arnold, F. H. (1994), J. Chromatogr. A. 662(1), 13–26.CrossRefGoogle Scholar
  26. 26.
    Todd, R. J., Johnson, R. D., and Arnold, F. H. (1994), J. Chromatogr. A. 662(1), 13–26.CrossRefGoogle Scholar
  27. 27.
    Sedlacek, J. and Nondek, L. (1985), J. High Resol. Chromastogr. 8(7), 364–365.CrossRefGoogle Scholar
  28. 28.
    Sircar, S. (1995), AIChE J. 41(5), 1135–1145.CrossRefGoogle Scholar
  29. 29.
    Johnson, R. D. and Arnold, F. H. (1995), Biochimica et Biophys. Act. 1247(2), 293–297.Google Scholar
  30. 30.
    Renard, J., Vidal-Madjar, C., Sebille, B., and Lapresle, C. (1995), J. Mol. Recogn. 8(1), 85–89.CrossRefGoogle Scholar
  31. 31.
    Li, S. J. and Liu, B. L. (2005), J. Graduate School Chin. Acad. Sci. 22(2), 179–186.Google Scholar
  32. 32.
    Gritti, F. and Guiochon, G. (2003), J. Colloid Interface Sci. 264(1), 43–59.CrossRefGoogle Scholar
  33. 33.
    Gritti, F., Götmar, G., Stanley, B. J., and Guiochon, G. (2003), J. Chromatogr. A. 988(2), 185–203.CrossRefGoogle Scholar
  34. 34.
    Piatkowski, W., Antos, D., Gritti, F., and Guiochon, G. (2003), J. Chromatogr. A. 1003(1), 73–89CrossRefGoogle Scholar
  35. 35.
    Ladiwala, A., Rege, K., Breneman, C. M., and Cramer, S. M. (2005), PNAS 102 (33), 11,710–11,715.CrossRefGoogle Scholar
  36. 36.
    Zhang, S. P. and Sun, Y. (2003), Ind. Eng. Chem. Res. 42(10), 1235–1243.CrossRefGoogle Scholar
  37. 37.
    Gerstner, J. A., Bell, J. A., and Cramer, S. M. (1997), Biophys. Chem. 52(1), 97–106.38.Google Scholar
  38. 38.
    Li, Y. and Pinto, N. G. (1995), J. Chromatogr. A. 702(2), 113–123.CrossRefGoogle Scholar

Copyright information

© Humana Press Inc 2006

Authors and Affiliations

  • Songjun Li
    • 1
  • Pingchu Chen
    • 1
  • Wuke Li
    • 1
  • Xiao Hao
    • 1
  • Guangfu Yang
    • 1
  1. 1.Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of ChemistryCentral China Normal UniversityWuhanP. R. China

Personalised recommendations