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Microbiologic oxidation of isosafrole into piperonal

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Abstract

The biotransformation of isosafrole by Cladosporium sphaerospermum yielded piperonal, which is a compound of great commercial importance in the flavor and fragrance industries. The experiments were performed in 500-mL conical flasks containing 100 mL of Czapek-modified medium in an orbital shaker with controlled agitation and temperature. Spores of C. sphaerospermum were used as inocula, and after 96 h of incubation the substrate was added to the culture. Samples of 2 mL were withdrawn at 24-h intervals and analyzed by gas chromatography, (GC) and/or GC/MS spectroscopy.

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Authors and Affiliations

  1. Instituto de Química, Universidade do Brasil, CT Bloco A Lab 641, 21945-970, Rio de Janeiro, RJ, Brazil

    Alberdan Silva Santos & Octavio A. C. Antunes

  2. Departamento de Engenharia Química, Universidade Federal do Pará, 66075-900, Belém, Pará, Brazil

    Alberdan Silva Santos

  3. Escola de Química, Universidade do Brasil, CT Bloco E, 21945-970, Rio de Janeiro, RJ, Brazil

    Nei Pereira Jr. & Iracema I. da Silva

  4. Laboratório de Coleção de Cultura de Fungos, Departamento de Micologia, Instituto Oswaldo Cruz, 21945-970, Rio de Janeiro, RJ, Brazil

    Maria Ines Sarquis

Authors
  1. Alberdan Silva Santos
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  2. Nei Pereira Jr.
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  3. Iracema I. da Silva
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  4. Maria Ines Sarquis
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  5. Octavio A. C. Antunes
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Correspondence to Octavio A. C. Antunes.

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Santos, A.S., Pereira, N., da Silva, I.I. et al. Microbiologic oxidation of isosafrole into piperonal. Appl Biochem Biotechnol 107, 649–657 (2003). https://doi.org/10.1385/ABAB:107:1-3:649

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  • DOI: https://doi.org/10.1385/ABAB:107:1-3:649

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