Chromatographia

, Volume 70, Issue 5–6, pp 933–937 | Cite as

Rapid Separation of Hydrophobic Compounds by UPLC: in Case of Bisindolylmaleimides, Indolocarbazoles or Fullerene C60 Derivatives

  • Manabu Nakazono
  • Yasuyuki Sato
  • Shigeo Hasegawa
  • Norimasa Arisuda
  • Aiko Miyamoto
  • Kiyoshi Zaitsu
Full Short Communication

Abstract

Rapid separation of hydrophobic compounds such as bisindolylmaleimides, indolocarbazoles or fullerene C60 derivatives by ultra performance liquid chromatography was developed. Bisindolylmaleimides and indolocarbazoles were separated within 7 and 5 min, respectively. The linear ranges for the determination of bisindolylmaleimides and indolocarbazoles were 1.25−500 pmol and 0.5−50 pmol per injection (r > 0.99), respectively. Fullerene C60 derivatives were separated within 9 min, and the linear range for the determination of fullerene C60 derivatives was 0.1−10 pmol per injection (r > 0.99).

Keywords

Ultra performance liquid chromatography Bisindolylmaleimide Indolocarbazole Fullerene 

Notes

Acknowledgments

We gratefully thank Waters (Tokyo, Japan) for the use of the Acquity UPLC system in the university program.

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Copyright information

© Vieweg+Teubner | GWV Fachverlage GmbH 2009

Authors and Affiliations

  • Manabu Nakazono
    • 1
  • Yasuyuki Sato
    • 1
  • Shigeo Hasegawa
    • 1
  • Norimasa Arisuda
    • 1
  • Aiko Miyamoto
    • 1
  • Kiyoshi Zaitsu
    • 1
  1. 1.Graduate School of Pharmaceutical SciencesKyushu UniversityFukuokaJapan

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