Chromatographia

, Volume 70, Issue 1–2, pp 281–285 | Cite as

Determination of Hepatotoxic Pyrrolizidine Alkaloids in Gynura segetum by MEKC

Full Short Communication

Abstract

A novel, rapid and sensitive micellar electrokinetic capillary chromatography method was developed for the separation and determination of two hepatotoxic pyrrolizidine alkaloids in Gynura segetum (Lour.) Merr. (Jusanqi) within 8 min. The method was successfully applied to the simultaneous determination of seneciphylline and senecionine in a Jusanqi sample.

Keywords

Column liquid chromatography Micellar electrokinetic capillary chromatography Seneciphylline and senecionine Lauric acid Gynura segetum 

Notes

Acknowledgments

This work was financially supported by Program for New Century Excellent Talents in University (NCET-06-0515) and National Basic Research Program of China (2005CB523402).

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Copyright information

© Vieweg+Teubner | GWV Fachverlage GmbH 2009

Authors and Affiliations

  1. 1.Pharmaceutical Informatics InstituteZhejiang University (Zijingang Campus)HangzhouPeople’s Republic of China
  2. 2.School of PharmacyJiangsu UniversityZhenjiangPeople’s Republic of China

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