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Chromatographia

, Volume 69, Issue 5–6, pp 571–573 | Cite as

Matrix Solid-Phase Dispersion Extraction for Analysis of Cypermethrin Residue in Cows’ Milk

  • Adriana N. Macedo
  • Ana R. A. Nogueira
  • Silvia Helena Govoni Brondi
Full Short Communication

Abstract

A method of extraction based on matrix solid-phase dispersion has been developed, optimized, and validated by chromatographic analysis of cypermethrin pesticide residues in samples of cows’ milk. Milk (0.25 g) was fortified with cypermethrin and blended with 1 g each of C18 (octadecylsilane) silica and Na2SO4 (anhydrous sodium sulfate), used to trap fats and water, respectively. The homogenized material was transferred to a commercial SPE cartridge containing 1 g activated Florisil with 5 mL acetonitrile. Cypermethrin was eluted under vacuum with 5 × 2 mL acetonitrile and the extract was concentrated to 1 mL and analyzed by gas chromatography–mass spectrometry. The limits of detection and quantification of the method were 0.025 and 0.08 mg kg−1, respectively.

Keywords

Gas chromatography Mass spectrometry Matrix solid-phase dispersion Milk Cypermethrin 

Notes

Acknowledgments

The authors are grateful to São Paulo State Research Foundation (FAPESP) for financial support of this research.

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Copyright information

© Vieweg+Teubner | GWV Fachverlage GmbH 2009

Authors and Affiliations

  • Adriana N. Macedo
    • 1
  • Ana R. A. Nogueira
    • 2
  • Silvia Helena Govoni Brondi
    • 2
  1. 1.Universidade Federal de São CarlosSão CarlosBrazil
  2. 2.Embrapa Pecuária SudesteSão CarlosBrazil

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