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Chromatographia

, 68:345 | Cite as

Extraction of Quinolizidine Alkaloids in Non Aqueous Basic Conditions: The Case of Spartium junceum Flowers

  • Emilia L. Belsito
  • Giuseppe Chidichimo
  • Maria L. Di Gioia
  • Antonella Leggio
  • Angelo Liguori
  • Francesca Perri
  • Carlo Siciliano
Original

Abstract

In this work the use of basic nonaqueous conditions is suggested as a general method for the extraction of quinolizidine alkaloids. The extraction of quinolizidine alkaloids from fresh flowers of Spartium junceum is performed in ethanolic basic conditions. The procedure is efficient and selective. The extract is essentially formed by N-formylcytisine, N-methylcytisine, cytisine and anagyrine. The method allows a high recovery of N-formylcytisine which becomes the predominant alkaloid in S. Junceum flowers.

Keywords

Gas chromatography–mass spectrometry Basic extraction N-Methylcytisine and N-formylcytisine Spartium junceum flowers 

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Copyright information

© Vieweg+Teubner | GWV Fachverlage GmbH 2008

Authors and Affiliations

  • Emilia L. Belsito
    • 1
  • Giuseppe Chidichimo
    • 2
  • Maria L. Di Gioia
    • 1
  • Antonella Leggio
    • 1
  • Angelo Liguori
    • 1
  • Francesca Perri
    • 1
  • Carlo Siciliano
    • 1
  1. 1.Dipartimento di Scienze FarmaceuticheUniversità della CalabriaArcavacata di Rende (CS)Italy
  2. 2.Dipartimento di ChimicaUniversità della CalabriaArcavacata di Rende (CS)Italy

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