Chromatographia

, Volume 64, Issue 9–10, pp 609–612 | Cite as

Sensitive Determination of Cyanide in Cigarette Smoke by Capillary GC with a MicroECD

  • Juan Xu
  • Hongwu Tong
  • Xiangyang Yan
  • Shan Du
  • Zhongda Yao
  • Shaomin Liu
Short Communication

Abstract

A sensitive method using capillary gas chromatography coupled with a micro electron capture detector (μECD) has been developed for the determination of cyanide in cigarette smoke. The procedure is based upon the conversion of cyanide to cyanogen chloride by chloramine-T. Cyanogen chloride, dissolved in n-hexane, was analyzed by GC–μECD. Under optimum conditions, the detector response was linear from 25.0 ng mL−1 to 15.0 μg mL−1 with relative standard deviation between 0.07 and 3.30%. Recovery ranged from 86.0 to 116.0%. The method was shown to be precise, accurate and linear over the range of concentration of analytes.

Keywords

Gas chromatography Capillary column Cyanide in cigarette smoke 

Notes

Acknowledgement

This work was supported by the Technology Center of Hefei Cigarette Factory, China.

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Copyright information

© Friedr. Vieweg & Sohn Verlag/GWV Fachverlage GmbH 2006

Authors and Affiliations

  • Juan Xu
    • 1
    • 2
  • Hongwu Tong
    • 1
  • Xiangyang Yan
    • 1
  • Shan Du
    • 3
  • Zhongda Yao
    • 3
  • Shaomin Liu
    • 1
  1. 1.Research Center of Tobacco and HealthUniversity of Science and Technology of ChinaHefeiChina
  2. 2.Department of ChemistryUniversity of Science and Technology of ChinaHefeiChina
  3. 3.Technology Center of Hefei Cigarette Factory of ChinaHefeiChina

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