Chinese Science Bulletin

, Volume 50, Issue 17, pp 1869–1873 | Cite as

A tetrairon(III) complex recognizing protein structures via a hydrolytic pathway

  • Pan Qunhui
  • Jiang Wei
  • Wang Ming
  • Liao Zhanru
  • Liu Changlin


There might be significant differences in the rate and efficiency in the metal complex-mediated hydrolytic reactions of proteins belonging to the different structural patterns. The tetrairon(III) complex [Fe4(NTB)42-O)24-Suc)] 6+, as a promoter in protein hydrolysis, is sensitive to α-helices in proteins, indicating that some metal complexes, as artificial proteolytic agents, could be used as a new hydrolytic probe of protein structures.


tetrairon complex hydrolysis α-helix structural probe 


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Copyright information

© Science in China Press 2005

Authors and Affiliations

  • Pan Qunhui
    • 1
  • Jiang Wei
    • 1
  • Wang Ming
    • 2
  • Liao Zhanru
    • 2
  • Liu Changlin
    • 1
  1. 1.Department of ChemistryHuazhong University of Science and TechnologyWuhanChina
  2. 2.Department of ChemistryHuazhong Normal UniversityWuhanChina

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