Skip to main content
SpringerLink
Log in

Time resolve study on isopropyl-ether porphyrindiol

  • Published:
Science in China Series B: Chemistry Aims and scope Submit manuscript

Abstract

A novel fat-soluble porphyrin derivative—isopropyl-ether porphyrindiol (IPEP) has been investigated using the nanosecond laser photolysis and pulse radiolysis. In acetonitrile, IPEP-excited triplet state shows two relative absorption areas peaking at 320 and 430 nm, molar extinction coefficients by energy transfer method (in benzene solution) are proved to be ε (315) = 1.07}105, ε (450)=3.3}104 L3 · mo-1 · cm-1 and the excited triplet state quantum yield by comparative method is 0.18. Laser photolysis of IPEP in dGMP-containing solution shows that the triplet state cannot excite/oxidize dGMP via the energy/electron transfer process.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Dong Run’an, Qiu Yong, Song Xinqi, Photooxidation of the biomolecular by porphyrin compounds, Progress in Chemistry (in Chinese), 1998,10(1): 45–53.

    CAS  Google Scholar 

  2. Silvester, J. A., Timmins, G. S., Davies, M. J., Photodynamically generated bovine serum albumin radicals: Evidence for damage transfer and oxidation at cysteine and tryptophan residues, Free Radical Biology & Medicine, 1998, 24(5): 754–766.

    Article  CAS  Google Scholar 

  3. Tadashi, U., Hiroshi, T., Keiji, K. et al., Effects of UV-sensitization of hemoporphyrin on lipid hydroperoxides in erythrocytes and on their hemolysis, J. Toxicol. Environ. Health, 1997,43(2): 101–107.

    Google Scholar 

  4. Croke, D. T., Perrouaut, L., Sari, M. A. et al., Structure-activity relationship for DNA photocleavage by cationic porphyrins, J. Photochem. Photobiol. B: Biol., 1993, 18: 41–50.

    Article  CAS  Google Scholar 

  5. Chatterjee, S. R., Shetty, S. J., Devasagayam, T. P. A. et al., Photocleavage of plasmid DNA by the porphyrin meso-tetrakis[4-(carboxymethyleneoxy)phenyl]porphyrin, J. Photochem. Photobiol. B: Biol., 1997, 41: 128–135.

    Article  CAS  Google Scholar 

  6. Zuo, Z. H., Yao, S. D., Jian, J. et al., Laser photolysis of cytosine, cytidine and dCMP in aqueous solution, J. Photochem. Photobiol. B: Biol., 1992, 15: 215–222.

    Article  CAS  Google Scholar 

  7. Hou, H. Q., Liu, Z. X., Mao, D. M. et al., Generation of the C60 fullence radical cation via electron transfer reaction: A pulse radiolysis study, Chem. Phys. Lett., 1993, 203: 555–559.

    Article  CAS  Google Scholar 

  8. Poletti, A., Murgia, S. M., Cannistraro, S., Laser flash photolysis of the hematoporphyrin-β-carotene system, Photobiochem. and Photobiophys., 1981, 2: 167–172.

    CAS  Google Scholar 

  9. Wilkinson, F., Farmilo, A., Mechanism of quenching of the triplet states of organic compounds by tris-(β-diketonato) complexes of iron (III), ruthenium (III) and aluminum (III), J. Chem. Soc. Faraday Trans. II, 1976, 72(3): 604–618.

    Article  CAS  Google Scholar 

  10. Wang, W. F., Luo, J., Zuo, Z. H. et al., Novel transient species of DNA bases from laser photolysis, Science in China, Series B, 1993, 36(12): 1466–1475.

    CAS  Google Scholar 

  11. Wood, P. D., Redmond, R. W., Triplet state interactions between nucleic acid bases in solution at room temperature: Intermolecular energy and electron transfer, J. Am. Chem. Soc., 1996, 118: 4256–4263.

    Article  CAS  Google Scholar 

  12. Land, E. J., Sykes, A., Truscott, T. G., Metastable state of β-carotene excited by pulse radiolysis, Photochem. Photobiol., 1971, 13:311–320.

    Article  CAS  Google Scholar 

  13. Compton, R. H., Grattan, K. T. V., Morrow, T., Extinction coefficients and quantum yields for triplet-triplet absorption using laser flash photolysis, J. Photochem., 1980, 14: 61–66.

    Article  CAS  Google Scholar 

  14. Das, P. K., Encinas, M. V., Scaiano, J. C., Intramolecular energy transfer in polymers containing benzoyl and naphthalene moieties, J. Am. Chem. Soc., 1981, 103: 4154–4162.

    Article  CAS  Google Scholar 

  15. Amand, B., Bensasson, R., Determination of the triplet quantum yields by laser flash absorption spectroscopy, Chem. Phys. Lett., 1975, 67: 44–46.

    Article  Google Scholar 

  16. Hideho, M., Atushi, N., Mamiru, T. et al., Reactions of metal-substituted myoglobins with excess electrons studied by pulse radiolysis and low-temperature gamma-radiolysis, Radiat. Phys. Chem., 1990, 36(6): 689–695.

    Google Scholar 

  17. Gut, I. G., Wood, P. D., Redmond, R. W., Interaction of triplet photosensitizers with nucleotides and DNA in aqueous solution at room temperature, J. Am. Chem. Soc., 1996, 118: 2366–2373.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Radiation Chemistry, Shanghai Institute of Nuclear Research, Chinese Academy of Sciences, 201800, Shanghai, China

    Lianwen Zhang, Side Yao & Weizhen Lin

  2. Department of Chemistry, Liaocheng University, 252059, Liaocheng, China

    Lianwen Zhang

  3. Department of Radiation Medical, Second Military Medical University of Shanghai, 200433, Shanghai, China

    Zhilong Chen

Authors
  1. Lianwen Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Side Yao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Weizhen Lin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zhilong Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Side Yao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhang, L., Yao, S., Lin, W. et al. Time resolve study on isopropyl-ether porphyrindiol. Sc. China Ser. B-Chem. 46, 51–56 (2003). https://doi.org/10.1360/03yb9008

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1360/03yb9008

Keywords

Search

Navigation