Science in China Series B: Chemistry

, Volume 46, Issue 1, pp 51–56 | Cite as

Time resolve study on isopropyl-ether porphyrindiol

  • Lianwen Zhang
  • Side Yao
  • Weizhen Lin
  • Zhilong Chen
Article
  • 18 Downloads

Abstract

A novel fat-soluble porphyrin derivative—isopropyl-ether porphyrindiol (IPEP) has been investigated using the nanosecond laser photolysis and pulse radiolysis. In acetonitrile, IPEP-excited triplet state shows two relative absorption areas peaking at 320 and 430 nm, molar extinction coefficients by energy transfer method (in benzene solution) are proved to be ε (315) = 1.07}105, ε (450)=3.3}104 L3 · mo-1 · cm-1 and the excited triplet state quantum yield by comparative method is 0.18. Laser photolysis of IPEP in dGMP-containing solution shows that the triplet state cannot excite/oxidize dGMP via the energy/electron transfer process.

Keywords

laser photolysis pulse radiolysis excited triplet state photodynamic therapy isopropyl- ether porphyrindiol 

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Copyright information

© Science in China Press 2003

Authors and Affiliations

  • Lianwen Zhang
    • 1
    • 2
  • Side Yao
    • 1
  • Weizhen Lin
    • 1
  • Zhilong Chen
    • 3
  1. 1.Laboratory of Radiation Chemistry, Shanghai Institute of Nuclear ResearchChinese Academy of SciencesShanghaiChina
  2. 2.Department of ChemistryLiaocheng UniversityLiaochengChina
  3. 3.Department of Radiation MedicalSecond Military Medical University of ShanghaiShanghaiChina

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