Chinese Science Bulletin

, Volume 48, Issue 21, pp 2386–2390 | Cite as

A novel theoretical model for mass transfer of hollow fiber hemodialyzers

  • Weiping Ding
  • Liqun He
  • Gang Zhao
  • Zhiquan Shu
  • Shuxia Cheng
  • Dayong Gao


A novel theoretical model for mass transfer of hollow fiber bundles in hemodialyzers is presented. In the model, a hemodialyzer is considered as a porous zone which is composed of two non-interpenetrating porous flow zones. Firstly, the dialysate side (shell side) is thought as a porous medium zone. Then by solidifying the dialysate flow zone and the occupied zone by hollow fiber membrane, the rest zone of hemodialyzer (i.e. blood side or lumen side) is considered as a porous medium zone too. Finally, the interface of the two flow zones is the fiber membrane through which mass transfer is performed. The dialysate and blood flows are all described by Navier-Stokes equations with Darcy momentum source terms. Kedem-Katchalsky equations as other source terms are added into Navier-Stokes equations to simulate the permeating flux through the membrane. All equations must be coupled together in the process of computing. The model is validated by the experimental data in literature. The simulative results show that the predicted clearances agree well with the experimental data, and the model in this paper is better than other models for the forecast of clearance.


porous media mass transfer hollow fiber clearance hemodialyzer 


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Copyright information

© Science in China Press 2003

Authors and Affiliations

  • Weiping Ding
    • 1
  • Liqun He
    • 1
  • Gang Zhao
    • 1
  • Zhiquan Shu
    • 1
  • Shuxia Cheng
    • 1
  • Dayong Gao
    • 1
    • 2
  1. 1.Department of Thermal Science & Energy EngineeringUniversity of Science & Technology of ChinaHefeiChina
  2. 2.Department of Mechanical EngineeringUniversity of KentuckyLexingtonUSA

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