Skip to main content
SpringerLink
Log in

Deveoopment of myofibroblasts from human bone marrow mesenchymal stem cells cocultured with human colon carcinoma cells and TGF beta 1

  • Letter to the Editor
  • Scientific Reports
  • Published:
In Vitro Cellular & Developmental Biology - Animal Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Bhiavegato, A.; Bochaton-Piallat, M.-L.; D'Amore, E., et al. Expression of myosin heavy chain isoforms in mammary epithelial cells and in myofibroblasts from different fibrotic settings during neoplasia. Virchows Arch. 426:77–86; 1995.

    Google Scholar 

  • Clark, B. R.; Keating, A.. Biology of bone marrow stroma. Ann. N.Y. Acad. Sci. 770:70–78; 1995.

    Article  PubMed  CAS  Google Scholar 

  • Eglitis, M. A.; Mezey, E.. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice. Proc. Natl. Acad. Sci. USA 94:4080–4085; 1997.

    Article  PubMed  CAS  Google Scholar 

  • Emura, M.; Ochiai, A.; Singh, G., et al. In vitro reconstitution of human respiratory epithelium. In Vitro Cell. Dev. Biol.—Animal 33:602–605; 1997.

    CAS  Google Scholar 

  • Ferrari, G.; Cusella-De Angelis, G.; Coletta, M., et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 279:1528–1530; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Fleming, J. E., Jr.; Haynesworth, S. E.; Cassiede, P., et al. Monoclonal antibody against adult marrow-derived mesenchymal stem cells recognizes developing vasculature in embryonic human skin. Dev. Dyn. 212:119–132; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Gleave, M.; Hsieh, J.-T.; Gao, C., et al. Acceleration of human prostate cancer growth in vivo by factors produced by prostate and bone fibroblasts. Cancer Res. 51:3753–3761; 1991.

    PubMed  CAS  Google Scholar 

  • Jaiswal, N.; Haynewworth, S. E.; Caplan, A. I., et al. Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J. Cell. Biochem. 64:295–312; 1997.

    Article  PubMed  CAS  Google Scholar 

  • Lennon, D. P.; Haynesworth, S. E.; Young, R. G., et al. A chemically defined medium supports in vitro, proliferation and maintains the osteochondral potential of rat marrow-derived mesenchymal stem cells. Exp. Cell Res. 219:211–222; 1995.

    Article  PubMed  CAS  Google Scholar 

  • Majumdar, M. K.; Thiede, M. A.; Mosca, J. D., et al. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells. J. Cell. Physiol. 176;57–66 1998.

    Article  PubMed  CAS  Google Scholar 

  • Martin, M.; Pujuguet, P.; Martin, F.. Role of stromal myofibroblasts infiltrating colon cancer in tumor invastion. Pathol. Res. Pract. 192:712–717; 1996.

    PubMed  CAS  Google Scholar 

  • Masur, S. K.; Dewal H. S.; Dinh, T. T., et al. Myofibroblasts differentiate from fibroblasts when plated at low density. Proc. Natl. Acad. Sci. USA 93:4219–4223; 1996.

    Article  PubMed  CAS  Google Scholar 

  • Meister, P. Myofibroblasten Übersicht und Ausblick. Pathologe 19:187–193; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Ojeda-Uribe, M.; Brunot, A.; Lenat, A., et al. Failure to detect spindle-shaped fibroblastoid cell progenitors in PBPC collections. Acta Haematol. 90: 139–143; 1993.

    Article  PubMed  CAS  Google Scholar 

  • Pereira, R. F.; Halford, K.W.; O'Hara, M. D., et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice. Proc. Natl. Acad. Sci. USA 92: 4857–4861; 1995.

    Article  PubMed  CAS  Google Scholar 

  • Pereira, R. F.; O'Hara, M. D.; Laptev, A. V., et al. Marrow stromal cells as a source of progenitoir cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperface. Proc. Natl. Acad. Sci. USA 95:1142–1147; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Petersen, B. E.; Bowen, W. C.; Patrene, K. D., et al. Bone marrow as a potential source of hepatic oval cells. Science 284:1168–1170; 1999.

    Article  PubMed  CAS  Google Scholar 

  • Prockop, D. J.. Marrow stromal cells as stem cells for nonhemotopoietic tissues. Science 276:71–74; 1997.

    Article  PubMed  CAS  Google Scholar 

  • Rønnov-Jessen, L.; Petersen, O. W.; Koteliansky, V. E., et al. The origin of the myofibroblasts in breast cancer: recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells. J. Clin. Invest. 95:859–873; 1995.

    Article  PubMed  Google Scholar 

  • Schürch, W.; Seemayer, T. A.; Gabbiani, G.. The myofibroblast: a, quartercentury after its discovery. Am. J. Surg. Pathol. 22:141–147; 1998.

    Article  PubMed  Google Scholar 

  • Serini, G. Bochaton-Piallat, M.-L.; Ropraz, P., et al. The fibronectin, domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-β1. J. Cell Biol. 142: 873–881; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Sieuwerts, A. M.; Klijn, J. G. M.; Hernzen-Logmans, S. C., et al. Urokinase-type-plasminogen-activator(UPA) production by human breast (myo)fibroblasts in vitro: influence of transforming growth factor-β1(TGFβ1) compared with factor(s) released by human epithelial-carcinoma cells. Int. J. Cancer 76:829–835; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Valentich, J. D.; Popov, V.; Saada, J. I., et al. Phenotypic characterization of an intestinal subepithelial myofibroblast cell line. Am. J. Physiol. 272: C1513-C1524; 1997.

    PubMed  CAS  Google Scholar 

  • Van Nhieu, J. T.; Brochériou, I.; Préaux, A.-M., et al. Myofibroblasts and hepatocellular carcinoma: an in vivo and in vitro study. J. Hepatol. 29:120–128; 1998.

    Article  PubMed  CAS  Google Scholar 

  • Wilkins, B. S.; Jones, D. B.. Immunohistochemical characterization of intact stromal layers in long-term cultures of human bone marrow. Br. J. Haematol. 90:757–706; 1995.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Pathology Division, National Cancer Center Research Institute East, 6-5-1 Kashiwanoha Kashiwa-City, 277-0882, Chiba, Japan

    Makito Emura, Atsushi Ochiaai & Megumi Horino

  2. Institute of Experimental Pathology, Medical School Hannover, Carl-Neuberg-Str. 1, D-30625, Hannover, Germany

    Willi Arndt & Kenji Kamino

  3. Pathology Division, National Cancer Center Research Institute, 5-1-1 Tsukiji Chuo-ku, 104-0045, Tokyo, Japan

    Setsuo Hirohashi

Authors
  1. Makito Emura
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Atsushi Ochiaai
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Megumi Horino
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Willi Arndt
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Kenji Kamino
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Setsuo Hirohashi
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Emura, M., Ochiaai, A., Horino, M. et al. Deveoopment of myofibroblasts from human bone marrow mesenchymal stem cells cocultured with human colon carcinoma cells and TGF beta 1. In Vitro Cell.Dev.Biol.-Animal 36, 77–80 (2000). https://doi.org/10.1290/1071-2690(2000)036<0077:DOMFHB>2.0.CO;2

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1290/1071-2690(2000)036<0077:DOMFHB>2.0.CO;2

Keywords

Search

Navigation