Improving Symptoms and Quality of Life of Female Cancer Survivors: a Randomized Controlled Study
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Surgeons, along with the Centers for Disease Control and Prevention, emphasize the importance of managing symptoms and improving the quality of life of cancer survivors. A 2008 meta-analysis of mindfulness-based stress reduction (MBSR) concluded that this technique might improve patients’ adjustment to their disease. However, randomized controlled trials using standardized measures for evaluating MBSR are limited. The primary objective of this study was to evaluate, using valid and reliable measures, the effects of a unique, interactive, 8-week cancer recovery and wellness program on symptoms and quality of life of female cancer survivors.
Sixty-eight female cancer patients were randomized into either an intervention or waitlisted control group. Patients were evaluated using the Symptoms Checklist (SCL-90-R), the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-30), and the Symptoms of Stress Inventory (SOSI).
Of the participants, 70.6% were breast cancer survivors. Mean age was 57.5 years (treatment group) and 56.4 years (control group). Between-group demographic differences were not significant (P > 0.6). The treatment group improved significantly on the EORTC QLQ-30 (P = 0.005), on six of the eight SOSI subscales (P ≤ 0.049), and on both SCL-90-R subscales (P ≤ 0.023), while the control group did not improve on any of these measures (P > 0.2).
The MBSR-based cancer recovery and wellness intervention improved the symptoms and quality of life of this largely breast cancer survivor population across a variety of cancer symptoms and quality-of-life measures.
KeywordsCancer Survivor Breast Cancer Survivor Mindfulness Practice Treatment Group Patient Female Cancer Survivor
This study was funded in part by the 2010 Oakland University–William Beaumont Hospital Multidisciplinary Research Award. We gratefully acknowledge the study participants for their courage, determination, and openness.
Disclosure and Financial Support
The authors have no conflict of interest or commercial interests in the subject of study.
- 1.National Cancer Institute: Surveillance epidemiology and end results—survival and stage. http://www.seer.cancer.gov/statfacts/html/breast.html#survival (2008). Accessed 20 March 2011.
- 2.National Cancer Institute: Estimated US cancer prevalence counts: who are our cancer survivors in the U.S.? http://www.cancercontrol.cancer.gov/ocs/prevalence (2008). Accessed 20 March 2011.
- 3.American Cancer Society: Breast cancer facts & figures 2009–2010. http://www.cancer.org/acs/groups/content/@nho/documents/document/f861009final90809pdf.pdf (2010). Accessed 15 January 2011.
- 4.Stewart DE, Cheung AM, Duff S, Wong F, McQuestion A, Cheng T, et al. Attributions of cause and recurrence in long-term breast cancer survivors. Psycho-oncology. 2001;10:179–183.Google Scholar
- 7.Brown JK, Byers T, Doyle C, Coumeya KS, Demark-Wahnefried W, Kushi LH, et al. Nutrition and physical activity during and after cancer treatment: an American cancer society guide for informed choices. CA A Cancer J Clin. 2003;53:268–291 (Information current as of 2 August 2010).Google Scholar
- 9.Cancer Survivorship. http://www.cdc.gov/cancer/survivorship/ (2009). Accessed 14 Jan 2009.
- 11.National Comprehensive Cancer Network: 10 Tips for breast cancer screening and early detection. http://www.nccn.com/cancer-by-type/330-tips-for-breast-cancer-screening.html (2011). Accessed 11 Nov 2010.
- 12.American Cancer Society: Breast cancer: early detection. http://www.cancer.org/Cancer/BreastCancer/MoreInformation/BreastCancerEarlyDetection/breast-cancer-early-detection-acs-recs-bse (2010). Accessed 17 April 2011.
- 13.National Cancer Institute: Breast cancer screening modalities. http://www.cancer.gov/cancertopics/pdq/screening/breast/healthprofessional/page4 (2008). Accessed 17 April 2011.
- 16.Leckie MS, Thompson E. Symptoms of stress inventory. Seattle: University of Washington; 1979.Google Scholar
- 18.Derogatis LR. The brief symptom inventory (BSI). Administration, scoring and procedures manual, 3rd edn. New York: National Computer Systems; 1993.Google Scholar
- 19.Kabat-Zinn J. Full catastrophe living: using the wisdom of your body and mind to face stress, pain, and illness. New York: Delta; 1990.Google Scholar
- 20.Goldberg N. Writing down the bones. Boston: Shambhala; 2005.Google Scholar
- 21.Remen R. Kitchen table wisdom. New York: Riverhead Books; 2006.Google Scholar
- 22.Cohen J. Statistical power analysis for the behavioral sciences. New York: Academic; 1988.Google Scholar
- 25.Proulx K. Integrating mindfulness-based stress reduction. Holist Nurs Prac. 2003;17:201–208.Google Scholar