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The Randomized Trial of Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemoperfusion: What It Does and Does Not Tell Us

  • Gastrointestinal Oncology
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References

  1. Sadeghi B, Arvieux C, Glehen O, et al. Peritoneal carcinomatosis from non-gynecologic malignancies: results of the EVOCAPE 1 multicentric prospective study. Cancer 2000;88:358–63

    Article  PubMed  CAS  Google Scholar 

  2. Elias D, Delperro J-P, Sideris L, et al. Treatment of peritoneal carcinomatosis arising from colorectal cancer: impact of complete cytoreductive surgery and difficulties in conducting randomized trials. Ann Surg Oncol 2004;11:518–21

    Article  PubMed  Google Scholar 

  3. Verwaal VJ, van Ruth S, de Bree E, et al. Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer. J Clin Oncol 2003;21:3737–43

    Article  PubMed  Google Scholar 

  4. Verwaal, VJ, Bruin S, Boot H, et al. 8-year follow up of a randomized trial: cytoreduction and hyperthemic intraperitoneal chemotherapy versus systemic chemotherapy in patients with peritoneal carcinomatosis of colorectal cancer. Ann Surg Oncol 2008

  5. Shen P, Levine EA, Hall J, et al. Factors predicting survival after intraperitoneal hyperthermic chemotherapy with mitomycin C after cytoreductive surgery for patients with peritoneal carcinomatosis. Arch Surg 2003;138:26–33

    Article  PubMed  CAS  Google Scholar 

  6. Schneebaum S, Arnold MW, Staubus A, et al. Intraperitoneal hyperthermic perfusion with mitomycin C for colorectal cancer with peritoneal metastases. Ann Surg Oncol 1996;3:44–50

    Article  PubMed  CAS  Google Scholar 

  7. Gleehen O, Kwiatkowski F, Sugarbaker PH, et al. Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer: a multi-institutional study. J Clin Oncol 2004;22:3284–92

    Article  Google Scholar 

  8. Smeenk RM, Verwaal VJ, Zoetmulder FA. Learning curve of combined mortality treatment in peritoneal surface disease. Br J Surg 2007;94:1408–14

    Article  PubMed  CAS  Google Scholar 

  9. Levine EA, Stewart JH, Russell G, et al. Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy for peritoneal surface malignancy: experience with 501 procedures. J Am Coll Surg 2007;204:943–55

    Article  PubMed  Google Scholar 

  10. Esquivel J, Sugarbaker P, Sticca R, et al. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Ann Surg Oncol 2007;14:128–33

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Surgical Oncology Service, Department of General Surgery, Wake Forest University, Medical Center Blvd., Winston-Salem, NC, 27157, USA

    Edward A. Levine MD

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  1. Edward A. Levine MD
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Correspondence to Edward A. Levine MD.

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Levine, E.A. The Randomized Trial of Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemoperfusion: What It Does and Does Not Tell Us. Ann Surg Oncol 15, 2633–2635 (2008). https://doi.org/10.1245/s10434-008-0108-7

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  • DOI: https://doi.org/10.1245/s10434-008-0108-7

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