References
Puri A, Agrawal MG, Shah M, et al. Giant cell tumor of bone in children and adolescents. J Pediatr Orthop 2007;27:635–9
Maki K, Harada T, Akiyami Y, et al. Giant cell tumor of the rib. Intern Med 2007;46:1151–2
Kapoor SK, Jain V, Agrawal M, et al. Primary malignant giant cell tumor of bone: a series of three rare cases. J Surg Orthop Adv 2007;16:89–92
Gleason BC, Kleinman PK, Debelenko LV, et al. Novel karyotypes in giant cell-rich lesions of bone. Am J Surg Pathol 2007;31:926–32
Jones KB, DeYoung BR, Morcuende JA, et al. Ethanol as a local adjuvant for giant cell tumor of bone. Iowa Orthop J 2006;26:69–76
Turcotte RE. Giant cell tumor of bone. Orthop Clin North Am 2006;37:35–51
Werner M. Giant cell tumour of bone: morphological, biological and histogenetical aspects. Int Orthop 2006;30:484–9
Hu Y, Yu S. Gene expression of osteoprotegerin and osteoclast differentiation factor in giant cell tumor. Zhonghua Bing Li Xue Za Zhi 2002;31:128–31
Atkins GJ, Kostakis P, Vincent C, et al. RANK Expression as a cell surface marker of human osteoclast precursors in peripheral blood, bone marrow, and giant cell tumors of bone. J Bone Miner Res 2006;21:1339–49
Hirai F, Nakayamada S, Okada Y, et al. Small GTPase Rho signaling is involved in beta1 integrin-mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor kappaB ligand on osteoblasts and osteoclast maturation. Biochem Biophys Res Commun 2007;356:279–85
Desai B, Rogers MJ, Chellaiah MA. Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells. Mol Cancer 2007;6:18–21
Brazier H, Stephens S, Ory S, et al. Expression profile of RhoGTPases and RhoGEFs during RANKL-stimulated osteoclastogenesis: identification of essential genes in osteoclasts. J Bone Miner Res 2006;21:1387–98
Holbourn KP, Sutton JM, Shore C, et al. Molecular recognition of an ADP-ribosyl transferase; clostridium botulinum C3 exoenzyme. Proc Natl Acad Sci 2005;102:5357–62
Harmey D, Stenbeck G, Nobes CD, et al. Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation. J Bone Miner Res 2004;19:661–7
Singh R, Wang B, Shirraikar A, et al. The IL-1 receptor and Rho directly associate to drive cell activation in inflammation. J Clin Invest 1999;103:1561–70
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Published by Springer Science+Business Media, Inc. © 2007 The Society of Surgical Oncology, Inc.
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Namazi, H. Botulinum Toxin: A Novel Adjuvant for Giant Cell Tumor. Ann Surg Oncol 15, 2066–2067 (2008). https://doi.org/10.1245/s10434-007-9770-4
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DOI: https://doi.org/10.1245/s10434-007-9770-4