How Many Nodes Need to be Removed to Make Esophagectomy an Adequate Cancer Operation, and Does the Number Change When a Patient has Chemoradiotherapy Before Surgery?

  • Jonathan C. Yeung
  • Manjit S. Bains
  • Arianna Barbetta
  • Tamar Nobel
  • Steven R. DeMeester
  • Brian E. Louie
  • Mark B. Orringer
  • Linda W. Martin
  • Rishindra M. Reddy
  • Francisco Schlottmann
  • Daniela MolenaEmail author
Thoracic Oncology


Introduction and Design

Node dissection during esophagectomy is an important aspect of esophageal cancer staging. Controversy remains as to how many nodes need to be resected in order to properly stage a patient and whether the removal of more nodes carries a stage-independent survival benefit. A review of the literature performed by a group of experts in the subject may help define a minimum accepted number of lymph nodes to be resected in both primary surgery and post-induction therapy scenarios.

Results and Conclusions

The existing evidence generally supports the goal of obtaining a minimum of 15 lymph nodes for pathological examination in both primary surgery and post-induction therapy scenarios.



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Copyright information

© Society of Surgical Oncology 2019

Authors and Affiliations

  • Jonathan C. Yeung
    • 1
  • Manjit S. Bains
    • 2
  • Arianna Barbetta
    • 2
  • Tamar Nobel
    • 2
  • Steven R. DeMeester
    • 3
  • Brian E. Louie
    • 4
  • Mark B. Orringer
    • 5
  • Linda W. Martin
    • 6
  • Rishindra M. Reddy
    • 5
  • Francisco Schlottmann
    • 2
  • Daniela Molena
    • 2
    Email author
  1. 1.Division of Thoracic Surgery, Department of SurgeryUniversity of TorontoTorontoCanada
  2. 2.Thoracic Service, Department of SurgeryMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  3. 3.Foregut and Thoracic Surgery, Division of Gastrointestinal and Minimally Invasive SurgeryThe Oregon ClinicPortlandUSA
  4. 4.Division of Thoracic SurgerySwedish Cancer InstituteSeattleUSA
  5. 5.Section of Thoracic Surgery, Department of SurgeryUniversity of MichiganAnn ArborUSA
  6. 6.Division of Thoracic SurgeryUniversity of Virginia School of MedicineCharlottesvilleUSA

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