Response to Letter to the Editor Regarding “A Randomized Trial Evaluating Bioimpedance Spectroscopy Versus Tape Measurement for the Prevention of Lymphedema Following Treatment for Breast Cancer: Interim Analysis”
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To the Editors:
We thank Dr. Barrio and colleagues for their letter which allows for further discussion of breast cancer-related lymphedema (BCRL) and the interim findings from the PREVENT trial.
We agree that there is a need for widespread adoption of BCRL screening (including baseline and follow-up screening) and to identify strategies that allow for BCRL screening in a variety of clinical environments. This was and remains a goal of the PREVENT study, to show that prospective surveillance, coupled with early intervention, reduces rates of chronic BCRL and the need for costly and time-consuming treatments such as complex decongestive physiotherapy (CDP).
It was understood during the design of the PREVENT study that the screening technique utilized would not be expected to change BCRL diagnosis rates. Rather, the hypothesis was that a more sensitive diagnostic technique might allow for detection at an earlier phase of the disease and reduce rates of chronic BCRL. The team decided to...
Chirag Shah is scientific consultant for ImpediMed Limited. Frank Vicini is scientific consultant and chief medical officer for ImpediMed Limited.
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