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Benign Papillary Breast Mass Lesions: Favorable Outcomes with Surgical Excision or Imaging Surveillance

  • Gillian KuehnerEmail author
  • Jeanne Darbinian
  • Laurel Habel
  • Karen Axelsson
  • Sherry Butler
  • Sharon Chang
  • Rhona Chen
  • Lou Fehrenbacher
Breast Oncology
  • 22 Downloads

Abstract

Background

There is no consensus regarding the management of benign papillary breast lesions diagnosed on image-guided core needle biopsy (IGCNB).

Methods

This is a retrospective review of 407 patients within Kaiser Permanente Northern California diagnosed between 2012 and 2013. The study focused on patients presenting with a mass lesion and who were diagnosed with a benign papillary breast lesion (BPBL) on IGCNB. Patients who did not have surgical excision of the IGCNB papilloma were followed for at least 2 years.

Results

A total of 327 patients (80%) underwent surgical excision, 61 patients (15%) had follow-up imaging, and 19 patients (5%) had no surgery or imaging. Overall among women with surgical excision, 9.5% had a high-risk lesion, 3.4% had in situ cancer, and 2.4% had invasive cancer. An upgrade to an in situ cancer or invasive cancer was more common among women with a lesion greater than 1 cm, a palpable breast mass, age > 50 years, or if the lesion was > 5 cm from the nipple. No cancers were diagnosed in 61 women followed by imaging surveillance.

Conclusions

This is the largest, single-cohort study of benign papillary mass lesions diagnosed on IGCNB. On surgical excision, the overall rate of upgrade to in situ cancer and invasive cancer was low, and almost all cancers diagnosed had favorable features. Because no cancers were found in women who were followed by imaging, we conclude that outcomes for BPBL diagnosed on IGCNB are favorable whether surgical excision or surveillance is the treatment choice.

Notes

Acknowledgment

This study was supported by a grant from the Kaiser Permanente Northern California Community Benefit Program.

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Copyright information

© Society of Surgical Oncology 2019

Authors and Affiliations

  • Gillian Kuehner
    • 1
    Email author
  • Jeanne Darbinian
    • 2
  • Laurel Habel
    • 2
  • Karen Axelsson
    • 3
  • Sherry Butler
    • 4
  • Sharon Chang
    • 5
  • Rhona Chen
    • 6
  • Lou Fehrenbacher
    • 7
  1. 1.Department of SurgeryThe Permanente Medical GroupVallejoUSA
  2. 2.Division of ResearchKaiser Permanente Northern CaliforniaOaklandUSA
  3. 3.Department of PathologyThe Permanente Medical GroupOaklandUSA
  4. 4.Department of RadiologyThe Permanente Medical GroupSouth San FranciscoUSA
  5. 5.Department of SurgeryThe Permanente Medical GroupFremontUSA
  6. 6.Department of SurgeryThe Permanente Medical GroupSouth San FranciscoUSA
  7. 7.Kaiser Permanente Oncology Clinical Trials Northern CaliforniaVallejoUSA

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